Evidence map›Paper›PMID 41179214›Full record

ReviewACS omega2025

Engineering Nanomaterials for Raman Bioimaging and Theranostics: Advances, Challenges, and Future Directions.

Nafih K A, Ashna Poulose, Amruth P, Sangamithra A S, Prashanth Kumar P N, Pramod K S

Abstract readReview
In one paragraph

Review in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nafih K AMaterial Science Research Laboratory, St Mary's College, Sulthan Bathery, University of Calicut, Wayanad, Kerala 673592, India.ORCID https://orcid.org/0009-0002-7786-9858
Ashna PouloseMaterial Science Research Laboratory, St Mary's College, Sulthan Bathery, University of Calicut, Wayanad, Kerala 673592, India.ORCID https://orcid.org/0000-0003-1259-9324
Amruth PMaterial Science Research Laboratory, St Mary's College, Sulthan Bathery, University of Calicut, Wayanad, Kerala 673592, India.
Sangamithra A SMaterial Science Research Laboratory, St Mary's College, Sulthan Bathery, University of Calicut, Wayanad, Kerala 673592, India.
Prashanth Kumar P NDepartment of Chemistry, DRM Science College, Davangere, Karnataka 577002, India.
Pramod K SMaterial Science Research Laboratory, St Mary's College, Sulthan Bathery, University of Calicut, Wayanad, Kerala 673592, India.ORCID https://orcid.org/0000-0003-2468-7196

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Raman imaging is rapidly advancing as a transformative platform for noninvasive, label-free molecular analysis across biomedical applications. Recent innovations in nanomaterials and photonics have enabled this technique to offer unprecedented spatial and chemical resolution. Advanced strategies such as cryogenic Raman microscopy, machine learning-enhanced hyperspectral analysis, and multimodal systems that integrate Raman spectroscopy with magnetic resonance imaging and photothermal therapy are now being developed to push the boundaries of imaging resolution and real-time analysis. This review focuses on integrating advanced Raman modalities with engineered nanostructures, particularly iron oxide-based hybrid nanoparticles, to achieve real-time, high-sensitivity imaging and targeted therapeutic delivery. Key challenges are critically addressed, including signal reproducibility, photodamage, and clinical translation. Finally, a conceptual framework is proposed linking material design, intelligent sensing, and adaptive therapeutics, positioning Raman imaging as a central component in next-generation theranostic platforms for precision healthcare.

Identifiers

PMID41179214
PMCPMC12573051

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.