Evidence map›Paper›PMID 41179167›Full record

ArticleACS omega2025

Effects of Combined Bacterial Infection and Radiation Injury on Biofluid Metabolite Profiles in the Murine Model.

Evan L Pannkuk, Anika Kot, Lorreta Yun-Tien Lin, Igor Shuryak, Eric Wang, Albert J Fornace, Heng-Hong Li

Abstract read
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Evan L PannkukDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, D.C., District of Columbia 20057, United States.ORCID https://orcid.org/0000-0002-4953-9715
Anika KotDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, D.C., District of Columbia 20057, United States.
Lorreta Yun-Tien LinDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, D.C., District of Columbia 20057, United States.
Igor ShuryakCenter for Radiological Research, Columbia University Irving Medical Center, New York, New York 10027, United States.
Eric WangCenter for Radiological Research, Columbia University Irving Medical Center, New York, New York 10027, United States.
Albert J FornaceDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, D.C., District of Columbia 20057, United States.
Heng-Hong LiDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, D.C., District of Columbia 20057, United States.

Funding

Sample Engineering CoreU19AI067773 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI AMUNDSON, SALLY A. · 2005 to 2024
$105.4M
Tissue Culture Shared ResourceP30CA051008 · NCI · GEORGETOWN UNIVERSITY · PI MARCUS S NOEL · 1990 to 2026
$71.5M
Metabolic impairment plays a critical role in radiation-induced T cell immune dysfunctionU01AI170024 · NIAID · GEORGETOWN UNIVERSITY · PI Albert J Fornace · 2022 to 2026
$3.4M
Development of a multiomic biodosimetry panel for use during sepsis and antibiotic treatmentR21AI193957 · NIAID · GEORGETOWN UNIVERSITY · PI Evan Pannkuk · 2025 to 2026
$312k
NCI NIH HHS P30 CA051008NIAID NIH HHS R21 AI193957NIAID NIH HHS U01 AI170024NIAID NIH HHS U19 AI067773
6 · The paper itself

Abstract

Rapid biodosimetry tools are needed to assess radiation exposure in scenarios complicated by secondary infections. This study evaluated how

Identifiers

PMID41179167
PMCPMC12572980

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.