Evidence map›Paper›PMID 41179107›Full record

ArticleCureus2025

Clinical Implications of Post-operative Haemoglobin Levels in Total Hip and Knee Arthroplasty.

Phillip A McCarthy, Mohammad Mirza, Mohammed Arafa, Irrum Afzal, Georgina Thompson, Leila Mohammadi, Natalia Chance, Syed S Ahmed

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Phillip A McCarthyTrauma and Orthopaedics, Maidstone and Tunbridge Wells National Health Service (NHS) Trust, Royal Tunbridge Wells, GBR.
Mohammad MirzaOrthopaedics, William Harvey Hospital, Ashford, GBR.
Mohammed ArafaTrauma and Orthopaedics, Maidstone and Tunbridge Wells National Health Service (NHS) Trust, Royal Tunbridge Wells, GBR.
Irrum AfzalOrthopaedics, South West London Elective Orthopaedic Centre, London, GBR.
Georgina ThompsonTrauma and Orthopaedics, Maidstone and Tunbridge Wells National Health Service (NHS) Trust, Royal Tunbridge Wells, GBR.
Leila MohammadiTrauma and Orthopaedics, Maidstone and Tunbridge Wells National Health Service (NHS) Trust, Royal Tunbridge Wells, GBR.
Natalia ChanceTrauma and Orthopaedics, Maidstone and Tunbridge Wells National Health Service (NHS) Trust, Royal Tunbridge Wells, GBR.
Syed S AhmedTrauma and Orthopaedics, Maidstone and Tunbridge Wells National Health Service (NHS) Trust, Royal Tunbridge Wells, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCurrent trends towards minimally invasive surgery and enhanced recovery encourage patients to mobilise and be discharged on the same day following total hip and knee arthroplasty (THA/TKA). The aim was to evaluate the value of current practice in measuring day 1 postoperative haemoglobin levels and stratify patient groups for whom this may be useful.

methodsThree hundred and five patients who underwent elective THA or TKA, over six months (June-December 2023 inclusive), at a single trust, were included. Variables including age, sex, pre-operative and post-operative haemoglobin, American Society of Anaesthesiologists classification, approach, tourniquet time and the use of a drain were recorded. Odds ratio analysis was used to assess factors that may increase the risk of post-operative anaemia.

resultsA total of 157 THAs and 148 TKAs were included; 156/305 (51%) were found to have haemoglobin levels that would be defined as anaemic post-operatively. Risk factors identified corresponding to post-operative anaemia include female gender and pre-operative anaemia. The use of a drain in TKA was associated with a statistically significant increase in the drop in haemoglobin (-14.7 vs. -11.7 g/L, p = 0.034), whereas the use of a tourniquet and patient age made no statistically significant difference. In the THA cohort, the anterolateral approach resulted in a greater drop in haemoglobin than the posterior approach (-15.7 vs. -11 g/L; p = 0.017). Only one patient in each group underwent transfusion (0.6% THA, 0.7% TKA).

conclusionOur data show that drops in haemoglobin that require intervention are rare and therefore carrying out day 1 post-operative haemoglobin levels is unnecessary for most patients. Pre-operative patient variables such as pre-existing anaemia and female gender are predictive of risk.

Indexed as

arthroplastyday-casehaemoglobinhipkneetransfusion

Identifiers

PMID41179107
PMCPMC12573042

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