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ArticleCureus2025

Morphometric Analysis of Mandibular Ramus Indices for Sex Prediction Using Digital Orthopantomograms (OPGs) and the GNU Image Manipulation Program (GIMP) Software.

Harshal R Thube, Vina Vaswani, Neelam Chandwani, Manish Shrigiriwar

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Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

4 authors.

Harshal R ThubeForensic Medicine, All India Institute of Medical Sciences, Nagpur, IND.
Vina VaswaniForensic Medicine, Yenepoya Medical College (Deemed to be University), Mangalore, IND.
Neelam ChandwaniDentistry, All India Institute of Medical Sciences, Nagpur, IND.
Manish ShrigiriwarForensic Medicine, All India Institute of Medical Sciences, Nagpur, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSex determination forms a crucial part of human identification in forensic medicine, anthropology, and clinical practice. The mandible is a durable and morphologically dimorphic bone, making it valuable for sex estimation. This is crucial in the forensic investigation. Advances in digital radiography and open-source software, such as the GNU Image Manipulation Program (GIMP), allow precise morphometric analysis, potentially enhancing the accuracy of forensic investigations.

aimThe study aimed to predict sex by calculating mandibular morphometric indices from digital orthopantomograms (OPGs) using the GIMP software in a central Indian population. MATERIALS AND

methodsThis cross-sectional study analyzed 500 archival OPGs (250 males and 250 females aged 20-40 years) obtained from the Department of Dentistry, AIIMS Nagpur. Four mandibular parameters, including condylar ramus height, projective ramus height, maximum ramus breadth, and minimum ramus breadth, were measured bilaterally using the GIMP software under double-blind conditions.

resultsAll four mandibular parameters showed statistically significant sexual dimorphism (p < 0.001), with males displaying larger linear dimensions than females. All four parameters showed significant dimorphism, with condylar ramus height and maximum ramus breadth contributing most strongly to sex prediction. The mean condylar ramus height was 58.89 mm in males and 52.36 mm in females; projective ramus height was 53.73 mm vs. 47.94 mm; maximum ramus breadth was 31.80 mm vs. 27.42 mm; and minimum ramus breadth was 25.55 mm vs. 23.12 mm. Regression analysis confirmed significant differences after adjusting for age. Discriminant function analysis demonstrated that condylar ramus height and maximum ramus breadth contributed most strongly to the sex classification.

conclusionMandibular morphometric indices obtained from OPGs using the GIMP software are reliable indicators of sex, with significant sexual dimorphism in the ramus dimensions. This cost-effective and reproducible method has the potential to enhance forensic identification protocols, especially where DNA or conventional methods are unavailable.

Indexed as

forensic anthropologygimp softwaremandiblemorphometryorthopantomogramsex determination

Identifiers

PMID41179102
PMCPMC12576373

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