Evidence map›Paper›PMID 41179072›Full record

ArticleCureus2025

Thyroid Cancer in a Psoriatic Patient Treated With Secukinumab: A Case Report and Literature Review.

Areej Alyousef, Hussein Attia, Mutlaq Alsulaili, Shehab Aldhafiri, Hamdy Sakr

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Areej AlyousefDermatology, Al-Jahra Hospital, Kuwait, KWT.
Hussein AttiaDermatology, Al-Jahra Hospital, Kuwait, KWT.
Mutlaq AlsulailiDermatology, Al-Jahra Hospital, Kuwait, KWT.
Shehab AldhafiriDermatology, Al-Jahra Hospital, Kuwait, KWT.
Hamdy SakrRadiation Oncology, Kuwait Cancer Control Center, Kuwait, KWT.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biologics are a key treatment option for managing chronic inflammatory and autoimmune diseases, especially moderate to severe psoriasis. While studies have not definitively proven a causal link between biologics and cancer, concerns remain regarding their potential association with an increased risk of certain malignancies. This report describes an observed temporal association in a patient with psoriasis who was treated with the interleukin-17A inhibitor secukinumab for four years and subsequently developed metastatic medullary thyroid cancer.

Indexed as

autoimmunebiologicscancercomplication of treatmentinterleukin-17amalignancymedullary thyroid carcinomaplaquepsoriasisthyroid cancer

Identifiers

PMID41179072
PMCPMC12574968

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.