ArticleCureus2025
Intra-cholecystic Tubulopapillary Neoplasm: Is Simple Cholecystectomy Enough?
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intracholecystic tubulopapillary neoplasm (ICPN) is a noninvasive, intraepithelial tumor presenting as a polypoid papillary mass arising from the gallbladder. Approximately 6.4% of all gallbladder neoplasms are associated with ICPNs. A young male presented with pain in the right hypochondrium and epigastrium. An abdominal ultrasound showed a 2.3 x 1.6 cm mass lesion in the gallbladder. Computed tomography (CT) of the abdomen showed an irregular polypoidal intraluminal soft tissue density of 21 x 17 mm in the fundus of the gallbladder. Endoscopic ultrasound (EUS) evaluation was suggestive of a gallbladder mass. On suspicion of carcinoma of the gallbladder, the patient underwent radical cholecystectomy with a 2 cm liver wedge with standard hepatoduodenal ligament, periportal, and retropancreatic lymphadenectomy with uneventful recovery. Postoperative histopathology revealed an ICPN with predominant intestinal morphology and low-grade dysplasia. All 16 lymph nodes were negative for malignancy. Dysplasia was present in the neck region but not in the cystic duct margin. ICPN is a rare entity to be recognized preoperatively. It is considered the counterpart of intraductal papillary mucinous neoplasm in the pancreatic cancer spectrum. Invasive carcinoma is present in almost half of the cases. It has a propensity for rapid conversion to carcinoma of the gallbladder. Preoperatively, if suspected, it should be treated with radical cholecystectomy for the potential of a cure for the invasive component as well as for staging purposes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.