ArticleCureus2025
Metastatic Mammary-Like Adenocarcinoma of the Vulva Responding to Cyclin-Dependent Kinase (CDK) Inhibitor: A Case Report and Literature Review.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mammary-like adenocarcinoma originating in the vulva is extremely rare, even rarer when metastasized at diagnosis. It may arise from the primitive mammary ridge or mammary-like glands of the skin in the anogenital region. We report a case of a 47-year-old woman with diffuse bone metastasis and a vulvar lesion compatible with mammary-type adenocarcinoma, with no evidence of primary breast cancer. Systemic treatment followed protocols for hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced breast cancer, using an aromatase inhibitor and ribociclib, resulting in a favorable clinical and metabolic response. Documenting this case contributes to the understanding and clinical management of this rare neoplasm.
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