Evidence map›Paper›PMID 41178897›Full record

ArticleJournal of medicine and life2025

Cerebrolysin treatment in a case of post-herpes simplex encephalitis with neuropsychiatric symptoms.

Young Seok Lee, Jinmi Seo, Soo Hwan Yim

Abstract readCase Reports
In one paragraph

Article in Journal of medicine and life, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Young Seok LeeDepartment of Neurology, Gangneung Asan Hospital, College of Medicine, Ulsan University, Gangneung, Republic of Korea.
Jinmi SeoDepartment of Neurology, Gangneung Asan Hospital, College of Medicine, Ulsan University, Gangneung, Republic of Korea.
Soo Hwan YimDepartment of Neurology, Gangneung Asan Hospital, College of Medicine, Ulsan University, Gangneung, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herpes simplex encephalitis (HSE) is a severe central nervous system (CNS) infection associated with cognitive decline, psychotic symptoms, and epilepsy. Despite aggressive antiviral and corticosteroid treatments, post-HSE complications remain challenging to manage. We report a case of a 33-year-old female patient with post-HSE neuropsychiatric symptoms who showed significant improvement following Cerebrolysin treatment. The patient was treated with acyclovir and dexamethasone in the acute phase, followed by Cerebrolysin administration in the post-acute phase. This case highlights the potential therapeutic role of Cerebrolysin in managing post-encephalitic cognitive dysfunction, underscoring the need for further studies.

Indexed as

Amino AcidsEncephalitis, Herpes SimplexAcyclovirAdultAntiviral AgentsFemaleHumansAcyclovirAmino AcidsAntiviral Agentscerebrolysincase reportCerebrolysinherpes simplex encephalitisneuropsychiatric symptoms

Identifiers

PMID41178897
PMCPMC12577782

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.