ArticleWorld journal of gastrointestinal surgery2025
Minimally invasive management of acute perforated cholecystitis: The role of percutaneous transhepatic cholecystostomy.
Article in World journal of gastrointestinal surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Interventional management of acute perforated cholecystitis: When is percutaneous transhepatic cholecystostomy a reasonable therapeutic option?World journal of gastrointestinal surgery · 2026Article
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6 authors.
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Abstract
backgroundAcute perforated cholecystitis (APC) is a serious complication of acute cholecystitis and is associated with significant morbidity and mortality, particularly in elderly or high-risk patients. While emergency cholecystectomy is the standard of care, it may not be feasible in unstable patients. Percutaneous transhepatic cholecystostomy (PTC) offers a minimally invasive alternative.
aimTo evaluate the safety and effectiveness of PTC as an initial treatment modality for APC.
methodsWe conducted a retrospective cohort study of patients diagnosed with APC between January 2017 and October 2022 at a single tertiary medical center. All patients underwent PTC as the initial intervention. Data collected included demographics, comorbidities, laboratory and imaging findings, complications, and clinical outcomes over a 24-month follow-up. Patients were stratified into two groups based on whether they subsequently underwent cholecystectomy.
resultsThirty patients underwent PTC for APC. Half of the patients (
conclusionPTC is a safe and effective initial treatment for APC, particularly in elderly and comorbid patients for whom surgery poses excessive risk. It provides clinical stabilization and may serve either as a bridge to delayed cholecystectomy or as definitive management in selected patients. These findings support the broader use of PTC in the management of APC, although larger prospective studies are warranted.
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