ArticleCase reports in infectious diseases2025
Macular Rash as a Presenting Symptom of Acute Q Fever: A Case Report.
Article in Case reports in infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Q fever is a globally distributed zoonotic infection caused by Case Presentation: A 63-year-old male metalworker was admitted with a 2-week history of high-grade fever, dyspnea, anorexia, intractable hiccups, and profound asthenia. Physical examination revealed a diffuse, nonpruritic, blanchable macular rash on the back and sacral region. Extensive microbiological and autoimmune investigations were negative. Chest imaging demonstrated bilateral pneumonia, mediastinal lymphadenopathy, and a small pericardial effusion. Skin biopsy showed mild acanthosis, dermal capillary congestion, and superficial lymphohistiocytic infiltrates. Serological testing confirmed acute Q fever, with elevated Phase II Discussion: This case highlights a rare parainfectious macular rash associated with acute Q fever-apparently the first reported in Italy. Cutaneous involvement in Q fever may represent a parainfectious immune-mediated reaction. Its nonspecific appearance and lack of a characteristic distribution pattern often delay diagnosis. Conclusion: Clinicians should maintain a high index of suspicion for
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