ArticlePlant biotechnology journal2026
Genome Assembly Revealed MdZAT5 Coordinates Anthocyanin Biosynthesis in Apple Fruit Peel and Flesh by Interacting With MdHY5.
Article in Plant biotechnology journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- From genome to gene module: decoding the BsAlfin2-BsTT2 regulatory network controlling low temperature-induced anthocyanin biosynthesis inHorticulture research · 2026Article
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Authors and funding
9 authors.
Funding
Abstract
Anthocyanins are plant pigments that contribute to fruit coloration and nutritional quality, yet the coordinated regulation of their accumulation in both peel and flesh remains elusive. Here, we present a haplotype-resolved genome of Malus cv. 'Royalty', a model cultivar with consistently red peel and flesh. A zinc-finger transcription factor, MdZAT5, was identified as a candidate regulator of anthocyanin biosynthesis, with two copies located on chromosomes 3 and 11 in each haplotype, as revealed by a well-assembled genome and transcriptomic profiling. Promoter and expression analyzes indicated that MdZAT5-3G acts downstream of light and MeJA signalling pathways. Transgenic analysis showed that MdZAT5-3G significantly promotes anthocyanin accumulation and upregulates anthocyanin biosynthesis genes such as MdCHS, MdCHI, and MdF3H, whereas its knockdown leads to reduced pigmentation. In contrast, MdZAT5-11G lacks regulatory function in both peel and flesh. Downstream binding assays confirmed that MdZAT5-3G directly binds to the promoters of anthocyanin biosynthetic genes, and biochemical assays revealed that its interaction with MdHY5 enhances promoter binding and transcriptional activation.
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