Evidence map›Paper›PMID 41178554›Full record

Trial reportStroke2026

Partnering With an Urban Hospital for Stroke Preparedness in the Emergency Department: SPEDI Randomized Controlled Trial.

Mellanie V Springer, Tiffany M Hodges, Devin L Brown, Robert Miller, Cristi Lanning, Lewis B Morgenstern, Michael Tupper, Marc A Zimmerman, Lesli E Skolarus

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Stroke, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mellanie V SpringerDepartment of Neurology and Stroke Program (M.V.S., T.M.H., D.L.B., R.M., L.B.M.), University of Michigan, Ann Arbor.ORCID 0000-0002-6281-0143
Tiffany M HodgesDepartment of Neurology and Stroke Program (M.V.S., T.M.H., D.L.B., R.M., L.B.M.), University of Michigan, Ann Arbor.
Devin L BrownDepartment of Neurology and Stroke Program (M.V.S., T.M.H., D.L.B., R.M., L.B.M.), University of Michigan, Ann Arbor.ORCID 0000-0002-9815-3421
Robert MillerDepartment of Neurology and Stroke Program (M.V.S., T.M.H., D.L.B., R.M., L.B.M.), University of Michigan, Ann Arbor.
Cristi LanningEastern Michigan University, Ypsilanti (C.L.).
Lewis B MorgensternDepartment of Neurology and Stroke Program (M.V.S., T.M.H., D.L.B., R.M., L.B.M.), University of Michigan, Ann Arbor.ORCID 0000-0002-5787-592X
Michael TupperDepartment of Emergency Medicine (L.B.M., M.T.), University of Michigan, Ann Arbor.
Marc A ZimmermanDepartment of Health Behavior and Health Equity, School of Public Health (M.A.Z.), University of Michigan, Ann Arbor.
Lesli E SkolarusDavee Department of Neurology, Stroke and Vascular Neurology, Northwestern University, Chicago, IL (L.E.S.).ORCID 0000-0002-3088-9838

Funding

Partnering with an Urban Safety Net Hospital to Deliver Stroke Preparedness in the Emergency DepartmentK01NS117555 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SPRINGER, MELLANIE V · 2020 to 2024
$1.2M
NINDS NIH HHS K01 NS117555
6 · The paper itself

Abstract

backgroundWe tested the Stroke Preparedness in the Emergency Department Intervention, an emergency department-based intervention that teaches stroke symptoms and the importance of calling 911, in a racially diverse community.

methodsThis was a National Institutes of Health-funded, single-center, participant-blinded parallel-group trial of adult emergency department patients randomized 1:1 to a brief pamphlet and video stroke preparedness intervention versus a general cardiovascular health control condition (Life's Simple 7; from February 2022 to August 2023). The primary outcome was intent to call 911 in response to 4 video vignettes (Video STAT instrument) depicting an actor having an acute stroke (stroke action score, range 0-8) at 1 month (delayed posttest). Secondary outcomes were recognition of the 4 videos depicting an acute stroke (stroke recognition score; range, 0-4) and the stroke action score immediately after treatment. Linear mixed models evaluated the association between intervention groups and each outcome, with adjustment for baseline characteristics, in a prespecified per-protocol analysis.

resultsOf the 353 participants randomized, 330 participants were included (159 in the intervention group, 171 in the control group, 61% female, 49% Black adults). The intervention group had a higher intent to call 911 than the control group on the immediate posttest (adjusted mean stroke action score difference, 1.14 points higher [95% CI, 0.78-1.50];

conclusionsAmong an adult emergency department population, a brief intervention increased intent to call 911 for stroke and increased recognition of stroke symptoms.

Indexed as

Emergency Service, HospitalHospitals, UrbanPatient Education as TopicStrokeAdultAgedFemaleHumansMaleMiddle Agedischemic strokeischemic stroke drug therapystrokestroke therapy

Identifiers

PMID41178554
PMCPMC12617342

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.