ReviewChemical record (New York, N.Y.)2026
Recent Advances in Metal-Based Catalysts for Nitrile Hydration to Amides: Mechanistic Aspects.
Review in Chemical record (New York, N.Y.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Photochemical Cascade Nitrile Activation via a Carbene-Nitrene Relay.Angewandte Chemie (International ed. in English) · 2026Article
- Recent Advances in Metal-Based Catalysts for Nitrile Hydration to Amides: Mechanistic Aspects.Chemical record (New York, N.Y.) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
The synthesis of amide building blocks is crucial for producing diverse amide-containing compounds such as peptides, proteins, and amino acids. The demand for innovative methods of amide bond derivatives, considered as vital nonclassical bioisosteres, is steadily increasing because of its pivotal role in drug development. A highly cost-effective and efficient approach for generating amide functional groups involves the metal-catalyzed hydration of nitriles, offering profound implications for both academic and industrial sectors. This review explores the recent successful catalytic systems, encompassing both homogeneous and heterogeneous solid catalysts that enhance the catalytic transformation of nitriles into amides. Furthermore, theoretical studies employing density functional theory calculations to elucidate the cooperative mechanism between the catalyst and the carbon-nitrogen bond in nitriles are overviewed.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.