ReviewCognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology2025
Brain-Behavior Relationships: Neural Mechanisms of Impulsivity and Compulsivity in Neuropsychiatric Disorders.
Review in Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Impulsivity, Compulsivity, Social Inappropriateness, and Other Neuropsychiatric Features in Cerebellar Histiocytosis.Cerebellum (London, England) · 2026Pooled it
- Impulse Control Disorders Are Independent of Parkinson Disease Motor Subtypes.medRxiv : the preprint server for health sciences · 2026Article
- Sex and age effects on binge eating spectrum disorders in young adults: a path analysis.Frontiers in psychology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Impulsivity and compulsivity are multidimensional transdiagnostic constructs with relevance to neurocognitive and other neuropsychiatric disorders. Broadly, impulsivity is the tendency to react quickly, while compulsivity is the tendency to perform repetitive and contextually inappropriate behaviors. Multiple cortical and subcortical neural pathways, neurotransmitter systems, synaptic plasticity changes, genetic factors, and epigenetic interactions influence decision-making, reward processing, and cognitive control. In this narrative review, we discuss the neural circuitry and disease mechanisms implicated in impulsivity and compulsivity, including emerging evidence of the cerebellum's influence on traditional reward circuitry. We also discuss current and emerging treatments, including neuromodulation targeted to the relevant network abnormalities. This high-level overview of impulsivity and compulsivity from a neurobiological perspective highlights the importance of furthering the understanding of the neural components and circuitry involved. Greater insight into the dynamics that modulate impulsivity and compulsivity may inform new therapeutics.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.