Evidence map›Paper›PMID 41177805›Full record

ArticleCurrent gene therapy2026

Foxp3

Nai Liang, Hui Chen, Yi Yang, Benlong Guo, Zehai Xu, Li Li, Yunfeng Jin

Abstract read
PubMed Publisher
In one paragraph

Article in Current gene therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nai LiangDepartment of Obstetrics and Gynecology, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, Jiangsu Province, 226001, China.
Hui ChenDepartment of Obstetrics and Gynecology, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, Jiangsu Province, 226001, China.
Yi YangDepartment of Obstetrics and Gynecology, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, Jiangsu Province, 226001, China.
Benlong GuoDepartment of Obstetrics and Gynecology, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, Jiangsu Province, 226001, China.
Zehai XuDepartment of Obstetrics and Gynecology, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, Jiangsu Province, 226001, China.
Li LiDepartment of Obstetrics and Gynecology, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, Jiangsu Province, 226001, China.
Yunfeng JinDepartment of Obstetrics and Gynecology, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, Jiangsu Province, 226001, China.

Funding

Nantong Health Commission scientific research MS2023017
6 · The paper itself

Abstract

introductionEpithelial Ovarian Cancer (EOC) is a highly aggressive gynecological malignancy with a high mortality rate primarily due to late-stage diagnosis and metastatic dissemination. Regulatory T cells (Tregs) have emerged as critical mediators of immune evasion, yet the role of Foxp3

methodsAn orthotopic EOC mouse model and in vitro co-culture systems were employed to investigate the effects of Foxp3

resultsFoxp3 DISCUSSION: These findings suggest that Foxp3

conclusionFoxp3

Indexed as

Carcinoma, Ovarian EpithelialForkhead Transcription FactorsMacrophagesOvarian NeoplasmsSirtuin 1T-Lymphocytes, RegulatoryAnimalsCell Line, TumorCell MovementDisease ProgressionFemaleHumansMAP Kinase Signaling SystemMiceSignal TransductionSTAT3 Transcription FactorForkhead Transcription FactorsFOXP3 protein, humanSIRT1 protein, humanSirtuin 1STAT3 protein, humanSTAT3 Transcription FactorFoxp3immunosuppressive macrophagemacrophagesOvarian cancerSirt1-ERK1/2-STAT3tregs

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.