Evidence map›Paper›PMID 41177766›Full record

ArticleCancer communications (London, England)2025

In vivo intratumoral heterogeneity in a dish: scalable forebrain organoid models of embryonal brain tumors for high-throughput personalized drug discovery.

Nicole C Riedel, Carolin Walter, Flavia W de Faria, Lea Altendorf, Paula Aust, Carolin Göbel, Archana Verma, Annika Ballast, Ivan Bedzhov, Rajanya Roy and 12 more

Abstract read
In one paragraph

Article in Cancer communications (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Nicole C RiedelDepartment of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany.ORCID https://orcid.org/0009-0002-4256-0746
Carolin WalterDepartment of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany.
Flavia W de FariaDepartment of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany.
Lea AltendorfDepartment of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Paula AustDepartment of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany.
Carolin GöbelDepartment of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Archana VermaDepartment of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany.
Annika BallastDepartment of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany.
Ivan BedzhovEmbryonic Self-Organization research group, Max Planck Institute for Molecular Biomedicine, Münster, Germany.
Rajanya RoyDepartment of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany.
Daniel MünterDepartment of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany.
Erik SchüftanDepartment of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany.
Thomas K AlbertDepartment of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany.
Claudia RössigDepartment of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany.
Pascal JohannPediatrics and Adolescent Medicine, Swabian Children's Cancer Center, Experimental pediatrics, University Hospital Augsburg, Augsburg, Germany.
Barbara von ZezschwitzDepartment of Pediatric Hematology and Oncology, Charité University Medicine, Berlin, Germany.
Sarah SandmannInstitute of Medical Data Science, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany.
Julian VargheseInstitute of Medical Data Science, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany.
Christian ThomasInstitute of Neuropathology, University Hospital Münster, Münster, Germany.
Ulrich SchüllerDepartment of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Jan M BruderDepartment of Cell and Developmental Biology, Max Planck Institute for Molecular Biomedicine, Münster, Germany.
Kornelius KerlDepartment of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany.

Funding

Deutsche Forschungsgemeinschaft INST 211/667-1Deutsche Forschungsgemeinschaft KE2004/4-1Deutsche Kinderkrebshilfe 70114460Fight Kids Cancer EpiRTFördergemeinschaft Kinderkrebszentrum HamburgMedizinerkollege Uni Münster 21-0007Medizinerkollege Uni Münster 22-0028
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41177766
PMCPMC12728470

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.