ArticleBMC oral health2025
The influence of incorporation of hydroxyapatite/collagen nanocomposite into glass ionomer cement on surface roughness, microhardness, and fluoride-ion release potential.
Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Evaluation of pediatric drugs on the surface roughness of primary enamel and restorative materials: an in vitro study.BMC oral health · 2026Article
- Surface Roughness and Color Stability of Conventional Glass Ionomer Cement Reinforced With a Nanofiller Synthesized by the Coprecipitation Method.International journal of biomaterials · 2026Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the effect of incorporation of 5 and 10 weight% of hydroxyapatite /collagen (HA/Col) nanocomposite with different ratios (50:50) and (70:30) to conventional glass ionomer cement (C-GIC) on surface roughness, microhardness, and fluoride-ion release. MATERIALS AND
methodsSeventy-five specimens were prepared using split Teflon mold (5 mm in diameter and 2 mm in thickness) and were randomly assigned to 5 different groups. Group I: control group of C-GIC, Group II: GIC modified with 5% HA/Col (50:50), Group III: GIC modified with 5% HA/Col (70:30), Group IV: GIC modified with 10% HA/Col (50:50), Group V: GIC modified with 10% HA/Col (70:30). The specimens were kept in deionized (DI) water and incubated at 37 °C.The DI water in each container was changed on the 1st, 7th, 14th, and 28th days. Fluoride ion release was assessed using the SPADNS colorimetric technique. Afterwards, a surface profilometer and a Vickers hardness tester were used to assess surface roughness and microhardness. Moreover, micromorphological analysis was assessed using SEM-EDX mapping.
resultsRegarding fluoride-ion release, mixed linear model revealed significant increase of fluoride-ion release in the 4 experimental groups compared to control one (p < 0.0001). Regarding surface roughness, and microhardness, one-way ANOVA test revealed a significant increase of surface roughness of experimental group of 10% HA/Col (50:50) compared to rest of groups, and significant increase of surface microhardness of all experimental groups compared to control one.
conclusionIncorporation of HA/Col nanocomposite into C-GIC cement showed promising improvements in surface hardness and fluoride ion release.
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