Evidence map›Paper›PMID 41176578›Full record

ArticleObesity surgery2025

Evaluation of Clinical Score, Esophageal Manometry and pH Monitoring before and after Conversion from Sleeve Gastrectomy to Roux-en-Y Gastric Bypass for Refractory Gastroesophageal Reflux Disease.

André Thá Nassif, Lucas Thá Nassif, Luís Sérgio Nassif, Enzo Thá de Oliveira, Chetan Parmar, Alexandre Coutinho Teixeira de Freitas

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Article in Obesity surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

André Thá NassifClinica Nassif, Curitiba - Paraná, Brazil. andrethanassif@gmail.com.
Lucas Thá NassifClinica Nassif, Curitiba - Paraná, Brazil.
Luís Sérgio NassifClinica Nassif, Curitiba - Paraná, Brazil.
Enzo Thá de OliveiraUniversidade Positivo, Curitiba, Brazil.
Chetan ParmarWhittington Hospital, London, United Kingdom.
Alexandre Coutinho Teixeira de FreitasPós Graduação de Clínica Cirúrgica, Federal University of Paraná, Curitiba, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionGastroesophageal reflux disease (GERD) after sleeve gastrectomy (SG) responds well to medical treatment. However, in refractory cases, surgical conversion to Roux-en-Y gastric bypass (RYGB) is considered the best option. The objective of this study was to evaluate the outcomes of sleeve-to-bypass conversion in patients with refractory GERD.

methodRetrospective analysis of prospectively collected patients undergoing this conversion, in which the clinical questionary (GERDq), esophageal manometry and pH monitoring were evaluated before and after 9 months after surgery.

resultsEleven patients with a mean age of 44.1 years were included, 10 of whom were female, with a mean BMI of 32.3 kg/m2 and a mean postoperative time of 6.1 years after SG. After conversion, the mean total weight loss was 14.1% and the mean total GERDq decreased from 35.4 to 8.3. There was no difference between the esophageal manometry results before and after surgery. There was a reduction in the mean DeMeester score at pH monitoring from 70 to 34, in the total number of distal reflux episodes from 43.8 to 19.1, and in the total number of proximal reflux episodes from 7.8 to 2.2. In esophageal manometry, the mean lower esophageal sphincter length before conversion was shorter in patients who maintained abnormal pH monitoring after surgery (2.3 vs. 4.4 cm).

conclusionSG to RYGB conversion may lower GERD, but it does not always resolve it. Although pH monitoring changes persisted, there was an improvement in the DeMeester score. The lower esophageal sphincter length may be associated with persistent reflux after conversion.

Indexed as

GastrectomyGastric BypassGastroesophageal RefluxObesity, MorbidAdultEsophageal pH MonitoringFemaleHumansMaleManometryMiddle AgedReoperationRetrospective StudiesTreatment OutcomeWeight LossBariatric surgeryBarrett’s esophagusGastric bypassGastroesophageal reflux diseaseRevisional surgerySleeve gastrectomy

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.