Evidence map›Paper›PMID 41176219›Full record

ArticleContemporary clinical trials2025

Rationale and design of the A-STAC study: A multi-stage, hybrid effectiveness-implementation trial to prevent and reduce racial disparities in postpartum hypertension.

Anne E Bowen, S Andrew Garbacz, Kristine M Alaniz, Micaela Berry-Smith, Daniel Bolt, Jill Strickland Denson, Harald Kliems, Megan Knutson Sinaise, Felice Resnik, Kara Hoppe

Abstract readClinical Trial Protocol
In one paragraph

Article in Contemporary clinical trials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Anne E BowenDepartment of Educational Psychology, University of Wisconsin-Madison, Madison, WI, United States of America. Electronic address: aebowen2@wisc.edu.
S Andrew GarbaczDepartment of Educational Psychology, University of Wisconsin-Madison, Madison, WI, United States of America.
Kristine M AlanizDepartment of Obstetrics and Gynecology, School of Medicine and Public Health, University of Wisconsin, Madison, WI, United States of America.
Micaela Berry-SmithPrevention Research Center, Department of Pediatrics, School of Medicine and Public Health, University of Wisconsin, Madison, WI, United States of America.
Daniel BoltDepartment of Educational Psychology, University of Wisconsin-Madison, Madison, WI, United States of America.
Jill Strickland DensonPrevention Research Center, Department of Pediatrics, School of Medicine and Public Health, University of Wisconsin, Madison, WI, United States of America.
Harald KliemsPrevention Research Center, Department of Pediatrics, School of Medicine and Public Health, University of Wisconsin, Madison, WI, United States of America.
Megan Knutson SinaiseDepartment of Obstetrics and Gynecology, School of Medicine and Public Health, University of Wisconsin, Madison, WI, United States of America.
Felice ResnikInstitute for Clinical and Translational Research, School of Medicine and Public Health, University of Wisconsin, Madison, WI, United States of America.
Kara HoppeDepartment of Obstetrics and Gynecology, School of Medicine and Public Health, University of Wisconsin, Madison, WI, United States of America.

Funding

University of Wisconsin Institute for Clinical and Translational ResearchUL1TR002373 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI ELIZABETH S BURNSIDE, Allan R. Brasier · 2017 to 2026
$75.9M
ACL HHS U48DP006793NCATS NIH HHS UL1 TR002373NCCDPHP CDC HHS U48 DP006793
6 · The paper itself

Abstract

backgroundHypertensive disorders of pregnancy are a leading cause of maternal and neonatal morbidity and mortality and are 60 % more common among Black birthing people than non-Black birthing people. Staying Healthy After Childbirth (STAC) is an evidence-based healthcare program that increases healthcare access by providing postpartum patients with a home blood pressure monitor and a healthcare team that remotely monitors and treats hypertension. This study adapts STAC to expand program reach for Black birthing people via implementation in community-based organizations.

methodThe study team is partnering with community-based organizations led by and/or serving Black birthing people and Black individuals with lived experiences of hypertension during pregnancy to inform care model adaptation. Guided by the Replicating Effective Programs Framework, the study will be conducted over three stages. The pre-implementation stage will consist of identifying adaptations to STAC to align with community values and priorities. We will apply these adaptations in rapid Plan-Do-Study-Act implementation cycles to create a finalized adapted STAC (A-STAC) program. The implementation stage will consist of delivering A-STAC through community-based organizations and evaluating A-STAC effectiveness, reach, and adoption. The maintenance and evolution stage will consist of identifying strategies for sustainment of A-STAC.

conclusionThis adapted intervention has the potential to decrease disparities in postpartum morbidity and mortality for Black birthing people and enhance generational health equity.

Indexed as

Black or African AmericanHealthcare DisparitiesHypertensionHypertension, Pregnancy-InducedAdultBlood Pressure Monitoring, AmbulatoryFemaleHealth Services AccessibilityHumansPostpartum PeriodPregnancyResearch DesignHypertensionPostpartumRacial disparities

Identifiers

PMID41176219
PMCPMC12747560

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.