ArticleHematology, transfusion and cell therapy
Integrating comprehensive care in the management of sickle cell disease patients in Nigeria.
Article in Hematology, transfusion and cell therapy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Renal care readiness and gaps in early detection of sickle cell nephropathy in children in North Kivu Province, Democratic Republic of the Congo: an exploratory cross-sectional study.BMC nephrology · 2026Article
- Transforming Hematology Care in Africa: Strategies for Enhanced Diagnosis and Treatment.Health science reports · 2026Article
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Authors and funding
8 authors.
Funding
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Abstract
introductionComprehensive sickle cell care is a holistic, multidisciplinary approach spanning from birth to adulthood. It includes newborn screening, routine investigations, medications, specific therapies and structured referrals. It is recognised since the 1972 US Sickle Cell Control Act and reinforced by the American Society of Haematology initiatives. This study evaluates the adoption of these strategies by physicians in Nigeria.
aimTo examine the extent to which comprehensive care strategies are implemented in the management of sickle cell disease by adult and paediatric haematologists in Nigeria. METHODOLOGY: This cross-sectional study was conducted from September to November 2022 across six tertiary hospitals. An adapted and pretested primary care assessment tool was used to collect data on physician demographics and strategic components of comprehensive care. Descriptive statistics and chi-square tests were used to analyse the data.
resultsA total of 157 doctors participated with most working in tertiary hospitals. Folic acid and proguanil hydrochloride were the most prescribed drugs; fewer than 50% used hydroxyurea. A complete blood count was the most requested investigation with 58% routinely scheduling investigations. Adult haematologists ordered more echocardiograms and paediatric haematologists requested more transcranial Dopplers. Adult haematologists referred more across specialities (p-value = 0.0001). All participants routinely counselled patients on clinic attendance, medication adherence and healthy lifestyle practices.
conclusionKey components of comprehensive care are practised at varying levels by health professionals in Nigeria, mainly in urban/tertiary hospitals. To strengthen nationwide delivery of care, health policies should prioritise equitable workforce distribution and integration of additional services, like neonatal screening and emerging therapies.
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