Evidence map›Paper›PMID 41175318›Full record

ArticleEcoHealth2026

First Pandemic blaCTX-M-8-Producing ST224 E. coli in Brazilian Sheep: Resistance and Genomic Traits.

Amanda V Peyser, Andressa Gonçalves, Amanda Haisi, João Pessoa Araújo, Raquel F S Raimondo, Marcos B Heinemann, Adriana Cortez, Natalia C Gaeta

Abstract read
PubMed Publisher
In one paragraph

Article in EcoHealth, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Amanda V PeyserPrograma de Pós-Graduação em Saúde Única, Universidade Santo Amaro., Prof. Enéas de Siqueira Neto, 340, Jardim das Imbúias, São Paulo, SP, 04829-300, Brazil.
Andressa GonçalvesNúcleo RuminAção, Universidade Federal do Rio Grande do Sul, Av. Farroupilha, Porto Alegre, Rio Grande do sul, Brazil.
Amanda HaisiUniversidade Estadual Paulist Júlio de Mesquita Filho, Alameda das Tecomarias, s/n - Chácara Capão Bonito, Botucatu, São Paulo, Brazil.
João Pessoa AraújoUniversidade Estadual Paulist Júlio de Mesquita Filho, Alameda das Tecomarias, s/n - Chácara Capão Bonito, Botucatu, São Paulo, Brazil.
Raquel F S RaimondoNúcleo RuminAção, Universidade Federal do Rio Grande do Sul, Av. Farroupilha, Porto Alegre, Rio Grande do sul, Brazil.
Marcos B HeinemannFaculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo., Av, Prof. Orlando Marques de Paiva, 87. Cidade Universitária, São Paulo, Brazil.
Adriana CortezPrograma de Pós-Graduação em Saúde Única, Universidade Santo Amaro., Prof. Enéas de Siqueira Neto, 340, Jardim das Imbúias, São Paulo, SP, 04829-300, Brazil.
Natalia C GaetaPrograma de Pós-Graduação em Saúde Única, Universidade Santo Amaro., Prof. Enéas de Siqueira Neto, 340, Jardim das Imbúias, São Paulo, SP, 04829-300, Brazil. ngaeta@prof.unisa.br.ORCID 0000-0001-6397-605X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Shiga toxin-producing E. coli (STEC) strains are particularly concerning due to their zoonotic potential and environmental persistence. Ruminants, especially sheep and cattle, serve as primary reservoirs, often shedding pathogenic strains asymptomatically and contributing to foodborne outbreaks through contamination of animal-derived products. This study aimed to characterize antimicrobial-resistant E. coli strains isolated from dairy sheep in Brazil, focusing on phylogenetic backgrounds, resistance profiles, and genomic features. From 65 rectal swab samples collected across five herds in two Brazilian states, 65 E. coli isolates were recovered. Of these, 27.7% showed antimicrobial resistance to at least one drug tested, and 32.3% were identified as STEC. Resistance was most frequently observed against sulfamethoxazole-trimethoprim, tetracycline, and gentamicin. Notably, one isolate (LZB-RS-110) exhibited an extended-spectrum β-lactamase (ESBL) phenotype and a multidrug-resistant profile. Whole-genome sequencing identified clinically relevant resistance genes (e.g., bla

Indexed as

beta-LactamasesEscherichia coli InfectionsSheep DiseasesShiga-Toxigenic Escherichia coliAnimalsAnti-Bacterial AgentsBrazilDrug Resistance, Multiple, BacterialPhylogenySheepAnti-Bacterial Agentsbeta-Lactamasesbla CTX-M-8genomic surveillanceone Healthwhole-genome sequencing

Identifiers

PMID41175318

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.