ReviewThe Saudi dental journal2025
Calcium sodium phosphosilicate toothpastes impact on the treatment of dentin hypersensitivity: an umbrella review.
Review in The Saudi dental journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Desensitizing toothpastes are considered an effective treatment option for managing dentin hypersensitivity (DH). This review evaluated existing systematic reviews and meta-analyses to determine the effectiveness of toothpastes containing calcium sodium phosphosilicate (CSPS) in managing DH. A comprehensive search was conducted in PubMed, Embase, Scopus, Cochrane, and Web of Science databases. Two reviewers performed study selection, data extraction, methodological quality assessment (using the AMSTAR 2 tool) and risk of bias (RoB; using the ROBIS tool) evaluation. The primary randomized clinical trials overlap was assessed using a citation matrix and calculating the overlap percentage, covered area (CA), and corrected covered area (CCA). A total of 5681 studies were identified and the full text of 85 studies were assessed. Finally, nine reviews were included in the umbrella review. A very high overlap was observed across primary studies. Eight studies had a low or critically low quality. Two reviews demonstrated a low RoB across all domains. CSPS-containing toothpastes were found to be more effective in relieving DH than placebo and negative controls. CSPS-containing toothpastes may be effective in relieving the pain associated with DH. However, the considerable heterogeneity and generally low methodological quality of the available evidence warrant cautious interpretation.
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