Evidence map›Paper›PMID 41175260›Full record

ReviewMetabolomics : Official journal of the Metabolomic Society2025

Metabolomic characterization of algal nutraceuticals to elucidate their biological activities.

Maghimaa Mathanmohun, Suresh Sagadevan, Is Fatimah, J Anita Lett, Noor Haida Mohd Kaus, Seema Garg, Mohammed A Al-Anber

Abstract readReview
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In one paragraph

Review in Metabolomics : Official journal of the Metabolomic Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Frontiers in pharmacology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maghimaa MathanmohunDepartment of Pathology, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, 602105, India. maghimaamm@gmail.com.
Suresh SagadevanNanotechnology & Catalysis Research Centre, University of Malaya, 50603, Kuala Lumpur, Malaysia. drsureshsagadevan@um.edu.my.
Is FatimahDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Islam Indonesia, Kampus Terpadu UII, Jl. Kaliurang Km 14, Sleman, Yogyakarta, Indonesia.
J Anita LettDepartment of Physics, Sathyabama Institute of Science and Technology, Chennai, Tamil Nadu, India.
Noor Haida Mohd KausNanoHybridMaterials Group, School of Chemical Sciences, Universiti Sains Malaysia, 11800, George Town, Penang, Malaysia.
Seema GargDepartment of Chemistry, Amity Institute of Applied Sciences, Amity University, Sector-125, Noida, 201313, Uttar Pradesh, India.
Mohammed A Al-AnberDepartment of Chemistry, Faculty of Sciences, Applied Science Private University, PO Box 166, Amman, 11931, Jordan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlgal nutraceuticals have emerged as the valuable bioresources due to their various chemical compositions and potential health benefits. Algae contain many bioactive compounds, including polyphenols, polysaccharides, omega-3 fatty acids, pigments, and vitamins, which are vital for the various biological processes in the human body. Understanding these complex metabolites is essential for their application in functional foods, dietary supplements, and pharmaceuticals. In this context, metabolomics provides a comprehensive approach for analyzing algal metabolic profiles and their nutritional and medicinal values. AIM OF REVIEW: This review explores the role of metabolomics in the evaluation and development of algal nutraceuticals. It focuses particularly on the identification and characterization of small-molecule metabolites in algae, offering insights into their functional properties and bioactivities. This review also discusses the integration of metabolomics with other omics technologies to achieve a holistic understanding of the metabolism of algae. KEY SCIENTIFIC CONCEPTS OF REVIEW: Metabolomic studies have successfully explored a wide range of bioactive compounds in algae with antioxidant, anti-inflammatory, anticancer, antibacterial, and neuroprotective activities. Techniques such as mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy have advanced the detection and quantification of metabolites with high sensitivity and resolution, respectively. Additionally, metabolomics aids to determine the quality biomarkers and the assessment of algal nutritional content. Integrating metabolomics with genomics, proteomics, and transcriptomics will further elucidate the metabolic pathways and regulatory networks in algae. This review highlights the critical role of metabolomics in maximizing the utilization of algae for health benefits.

Indexed as

Dietary SupplementsMetabolomicsAnimalsHumansAlgal nutraceuticalsAnticancerAnti-inflammatoryAntimicrobialAntioxidantBioactive compoundsMetabolomics

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.