Evidence map›Paper›PMID 41175251›Full record

ArticleInternational ophthalmology2025

Quantitative automated pupillometry in pseudoexfoliation and evaluation of contributory factors.

Paromita Dutta, Uttam Dhaka, Parul Jain, Sachin Verma, Palash Patni

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Article in International ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Paromita DuttaGuru Nanak Eye Centre, Maulana Azad Medical College, Maharaja Ranjit Singh Marg, New Delhi, India. mitad.4@gmail.com.
Uttam DhakaGuru Nanak Eye Centre, Maulana Azad Medical College, Maharaja Ranjit Singh Marg, New Delhi, India.
Parul JainGuru Nanak Eye Centre, Maulana Azad Medical College, Maharaja Ranjit Singh Marg, New Delhi, India.
Sachin VermaGuru Nanak Eye Centre, Maulana Azad Medical College, Maharaja Ranjit Singh Marg, New Delhi, India.
Palash PatniGuru Nanak Eye Centre, Maulana Azad Medical College, Maharaja Ranjit Singh Marg, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo study differences in automated pupillometry parameters between patients with Pseudoexfoliation (PEX) and healthy individuals, and to assess contributory parameters.

methodsForty phakic patients with PEX (with or without early-moderate glaucoma) were categorised into Affected (eyes with clinical signs of PEX present, n = 55 eyes) and Unaffected group (clinically normal fellow eyes, n = 23 eyes), along with 80 age-matched healthy controls. Participants were tested on an automated pupillometer. Static pupillometry was tested at high photopic (100 cd/m

resultsGlaucoma was present in 12.8% of PEX (n = 10). Static pupillary diameters (PD) were significantly different in both Affected and Unaffected groups of PEX, compared to controls. Both PEX groups showed significantly lower amplitude of contraction and percent pupillary contraction (p < 0.001), slower velocities of contraction and dilation (p < 0.001), and increased latency of contraction compared to controls (p = 0.001). The Affected and Unaffected groups did not differ in pupillometry parameters. Inferior quadrant RNFLT had a positive correlation with multiple pupillary parameters. An equation was derived by linear regression to predict MPD. MPD = 4.34 + 0.61 × Scotopic PD - 0.37 × Mesopic PD + 0.35 × Velocity of contraction.

conclusionAbnormal pupillary kinetics are present in both eyes of patients with PEX. PEX is associated with asymptomatic inferior quadrant RNFLT thinning. Pupillometry can be used to predict maximum pupillary dilation in PEX.

Indexed as

Exfoliation SyndromePupilAgedFemaleHumansIntraocular PressureIrisMaleMiddle AgedNerve FibersRetinal Ganglion CellsTomography, Optical CoherenceAutomated pupillometryMaximum pupillary dilationPseudoexfoliationRetinal nerve fibre layer

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.