Evidence map›Paper›PMID 41175209›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Association of operative-level segmental lordosis correction with reciprocal changes in sagittal and spinopelvic parameters after single-level lateral lumbar interbody fusion at L4-5.

Nafis B Eghrari, Jonathan J Lee, Winward Choy, Juan P Giraldo, Gabriella P Williams, Luke K O'Neill, James J Zhou, S Harrison Farber, Joseph M Abbatematteo, Jay D Turner and 1 more

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Nafis B EghrariDepartment of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, United States.
Jonathan J LeeDepartment of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, United States.
Winward ChoyDepartment of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, United States.
Juan P GiraldoDepartment of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, United States.
Gabriella P WilliamsDepartment of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, United States.
Luke K O'NeillDepartment of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, United States.
James J ZhouDepartment of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, United States.
S Harrison FarberDepartment of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, United States.
Joseph M AbbatematteoDepartment of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, United States.
Jay D TurnerDepartment of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, United States.
Juan S UribeDepartment of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, United States. neuropub@barrowneuro.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAssess the relationship between change in L4-5 segmental lordosis (SL) and its effect on clinical and radiographic parameters after lateral lumbar interbody fusion (LLIF) at L4-5.

methodsClinical scores and radiographic measurements were collected for patients who underwent single-level LLIF at L4-5 at a local institution between 2017 and 2022. Linear regression analysis was performed for changes in clinical and radiographic parameters as a function of change in SL.

resultsNinety-four patients were included in the analysis. Significant preoperative to postoperative increases occurred in L4-5 SL (P < 0.001), L2-3 SL (P = 0.04), anterior disc height (P < 0.001), posterior disc height (P < 0.001), neural foraminal height (P < 0.001), and T1-pelvic angle (P = 0.03). Significant decreases occurred postoperatively in L5-S1 SL (P < 0.001) and spondylolisthesis length (P < 0.001). Change in L4-5 SL was positively correlated with Δ lumbar lordosis (LL; P = 0.001), Δ distal LL (P < 0.001), Δ anterior disc height (P < 0.001), and Δ T5-T12 kyphosis (P = 0.04). Change in L4-5 SL was negatively correlated with Δ pelvic incidence-LL mismatch (P = 0.001) and Δ L5-S1 SL (P = 0.01).

conclusionLLIF at L4-5 induced greater L4-5 SL; this change was positively associated with changes in LL, distal LL, anterior disc height, and T5-T12 kyphosis, and negatively associated with changes in pelvic incidence-LL mismatch and L5-S1 SL. Potential compensatory changes proximal and distal to the LLIF level may depend on the amount of SL achieved at the operative level.

Indexed as

LordosisLumbar VertebraeSpinal FusionSpondylolisthesisAdultAgedFemaleHumansMaleMiddle AgedRadiographyRetrospective StudiesTreatment OutcomeAdjacent segmentFusionLordosisLumbarSagittal balance

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.