Evidence map›Paper›PMID 41175205›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Practice preference of thromboprophylaxis following spine surgery - an international expert survey of AO spine members.

Alexandro Dünki, Adrian Kohler, Hagen Bomberg, Mazda Farshad, Andreas K Demetriades, Sathish Muthu, Urs Eichenberger

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alexandro DünkiBalgrist University Hospital, Zurich, Switzerland. alexandro.duenki@balgrist.ch.
Adrian KohlerBalgrist University Hospital, Zurich, Switzerland. adrian.kohler@balgrist.ch.
Hagen BombergBalgrist University Hospital, Zurich, Switzerland. hagen.bomberg@balgrist.ch.
Mazda FarshadBalgrist University Hospital, Zurich, Switzerland.
Andreas K DemetriadesKnowledge Forum Degenerative, AO Spine International, AO Foundation, Davos, Switzerland.
Sathish MuthuKnowledge Forum Degenerative, AO Spine International, AO Foundation, Davos, Switzerland.
Urs EichenbergerBalgrist University Hospital, Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designInternational survey.

objectivesThromboprophylaxis after thoraco-lumbar spine surgery has been a source of controversy for decades. Clear evidence-based guidelines for the best prophylaxis modality are still missing. In this international survey, we asked spine surgeons about their clinical practices.

methodsA survey was distributed electronically to global members of the AO Spine community. The survey consisted of 27 questions of which 14 were analyzed in this study. Twelve questions addressed general information and two the way in which thromboprophylaxis was performed in patients with or without heightened risk of venous thromboembolism by using LMWH, UFH or other methods. We defined consensus for binary (yes/no) questions at > 80% or < 20%; intermediate consensus between 60 and 80% or 20-40%; an agreement between 40 and 60% was designated controversial.

resultsA total of 240 respondents between June 26, 2024 and July 10, 2024 were included. The distribution of regional practice was Asia Pacific (21%), Europe and Southern Africa (33%), Latin America (20%), Middle East and Northern Africa (15%), and North America (11%). The preferred method of thromboprophylaxis was controversial in patients without heightened risk of venous thromboembolism. In contrast, in patients with an increased risk of venous thromboembolism, an intermediate consensus of 75% was found for low molecular weight heparin only. However, pneumatic compression devices were the preferred method in high risk patients in North America.

conclusionsThe way in which thromboprophylaxis is carried out continues to be controversial. There is a need for more studies to build strong guidelines and standardize thromboprophylactic practice.

Indexed as

Orthopedic ProceduresPostoperative ComplicationsPractice Patterns, Physicians'SpineVenous ThromboembolismAnticoagulantsHeparin, Low-Molecular-WeightHumansSurveys and QuestionnairesAnticoagulantsHeparin, Low-Molecular-WeightBleedingMorbidityMortalitySpine surgeryThromboprophylaxisThrombosis

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.