ArticleJournal of anesthesia2026
Association between intraoperative inspired oxygen exposure and risk of postoperative pulmonary complications in abdominal surgery: a multi-center prospective cohort study.
Article in Journal of anesthesia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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7 authors.
Funding
Abstract
purposeThe impact of higher intraoperative oxygen administration increases the risk of postoperative pulmonary complications (PPCs) remains uncertain. This study aimed to investigate whether high supraphysiological oxygen exposure during abdominal surgery is associated with the development of PPCs.
methodsWe conducted a multi-center prospective cohort trial of adults scheduled for abdominal surgery under general anesthesia lasting at least two hours. Supraphysiological oxygen exposure was quantified as the area under the curve of the FiO
resultsAmong the 660 included patients (mean age, 58 years; 275 [41.7%] women; 468 [70.1%] at intermediate or high risk of PPCs), 163 (24.7%) experienced PPCs within the first 7 postoperative days. After adjusting for confounders, higher supraphysiological oxygen exposure was independently associated with PPCs (adjusted odds ratio, 1.21 [95% confidence interval, 1.09-1.35], P < 0.001).
conclusionsIn adult patients undergoing abdominal surgery under general anesthesia, intraoperative supraphysiological oxygen exposure was associated with an increased risk of PPCs.
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