ArticleJournal of assisted reproduction and genetics2026
Inflammatory proteomics of uterine fluid is potentially a non-invasive predictor for endometrial receptivity: a pilot study.
Article in Journal of assisted reproduction and genetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Non-invasive biomarkers in assisted reproductive technologies, current evidence, clinical utility and future perspectives.Frontiers in reproductive health · 2026Review
- Multidimensional regulatory architecture of endometrial receptivity and its translational implications for implantation failure.Frontiers in endocrinology · 2026Review
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Authors and funding
7 authors.
Funding
Abstract
purposeTo evaluate whether the inflammatory proteomics of uterine fluid is feasible in defining the endometrial receptivity phase.
methodsInflammatory proteomics of uterine fluid was measured using the OLINK Target-96 Inflammation panel. Endometrial receptivity testing (ERT) combined with endometrial dating was used to define the phase of endometrial receptivity. A predictive model based on proteomics of uterine fluid was established to predict the endometrial receptivity phase.
resultsThe inflammatory factors in uterine fluid were differentially expressed between the window of implantation (WOI) and displaced WOI groups; the displaced WOI group was characterized by increased expression of a variety of inflammatory factors. The predictive model established based on the top five differential proteins could classify the endometrial receptive phase. Transcriptomic data from endometrial tissues showed that the differential gene sets between different receptive phases were mostly enriched in immune-related processes, and the expression of immune-related genes in the WOI group was significantly lower than that in the displaced WOI group.
conclusionsDetecting inflammatory proteins from the uterine fluid using the OLINK inflammation panel is feasible and holds promise as a novel non-invasive method to define endometrial receptivity phases.
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