Evidence map›Paper›PMID 41175128›Full record

ArticleThe Journal of adolescent health : official publication of the Society for Adolescent Medicine2026

Parent-Adolescent Relationship Quality, Sexual Health Communication, and Willingness to Support Pre-Exposure Prophylaxis for HIV: A Qualitative Study.

Jack C Rusley, Amelia Knopf, Kate M Guthrie, Emily Toma, Renata Arrington-Sanders

Abstract read
In one paragraph

Article in The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Neighborhoods, Caregiver Sexuality Communication, and Sexual Health of Adolescents Involved in the Legal System.Journal of correctional health care : the official journal of the National Commission on Correctional Health Care · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jack C RusleyDivision of Adolescent Medicine, Department of Pediatrics, Alpert Medical School of Brown University, Providence, Rhode Island. Electronic address: jack_rusley@brown.edu.
Amelia KnopfDepartment of Community and Health Systems, Indiana University School of Nursing, Indianapolis, Indiana.
Kate M GuthrieDepartment of Psychiatry & Human Behavior, Alpert Medical School of Brown University, Providence, Rhode Island.
Emily TomaDivision of Infectious Disease, Department of Medicine, Alpert Medical School of Brown University, Providence, Rhode Island.
Renata Arrington-SandersDivision of Adolescent Medicine, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland.

Funding

Project-003U24HD089880 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HUDGENS, MICHAEL G, LAVANGE, LISA · 2016 to 2021
$44.3M
A family-based intervention to improve HIV pre-exposure prophylaxis uptake for adolescent sexual minority malesK23MH123335 · NIMH · RHODE ISLAND HOSPITAL · PI RUSLEY, JACK · 2020 to 2024
$843k
NICHD NIH HHS U24 HD089880NIMH NIH HHS K23 MH123335
6 · The paper itself

Abstract

purposePre-exposure prophylaxis (PrEP) for HIV is a safe and highly effective prevention method, yet use among U.S. adolescents at risk for HIV has been low. Little is known about how sexual health communication (SHC) and the quality of parent-adolescent relationships influence parents' hypothetical willingness to support their adolescent using PrEP.

methodsWe conducted 34 in-depth interviews with parents of adolescents recruited from four U.S. urban clinical sites between 2018 and 2019. We then used applied thematic analysis informed by two theories to determine parents' hypothetical willingness (more vs. less willing) and to identify related themes, focusing on differences between more versus less willing parents.

resultsParents were diverse with respect to race/ethnicity (68% Black/African American, 18% Hispanic). Most were cisgender men (44%) or women (41%). Approximately half (n = 19, 56%) were more willing. Four themes related to willingness were identified: (1) relationship quality, (2) acceptance of sexual and gender-diverse (SGD) identities, (3) sex positivity of SHC, and (4) general positivity about PrEP. Responses from more willing parents tended toward higher relationship quality, more acceptance of SGD identities, more sex positivity, and PrEP positivity; conversely, less willing parents tended toward the opposite ends of each theme. HIV risk perception did not consistently impact willingness, as both more and less willing parents largely perceived their adolescent's HIV risk as low. DISCUSSION: Parents who were more willing to support their adolescent hypothetically using PrEP tended to describe high-quality relationships, acceptance of SGD identities, sex positivity of SHC, and general positivity about PrEP.

Indexed as

HIV InfectionsParent-Child RelationsParentsPre-Exposure ProphylaxisSexual HealthAdolescentAdultCommunicationFemaleHumansInterviews as TopicMaleMiddle AgedQualitative ResearchSexual BehaviorUnited StatesAdolescentHIV preventionParentPre-exposure prophylaxisQualitative methods

Identifiers

PMID41175128
PMCPMC12704393

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.