Evidence map›Paper›PMID 41175009›Full record

SynthesisClinical anatomy (New York, N.Y.)2026

A Meta-Analysis and Simplified Nomenclature for Diagonal Coronary Artery and Ramus Intermedius Across Adult and Pediatric Hearts.

Yuqian Dai, Sabrina Constantini, Michael J Montalbano, Marios Loukas

Abstract readMeta-AnalysisReview
In one paragraph

Synthesis in Clinical anatomy (New York, N.Y.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yuqian DaiDepartment of Anatomical Sciences, St. George's University, School of Medicine, Grenada, West Indies.
Sabrina ConstantiniDepartment of Anatomical Sciences, St. George's University, School of Medicine, Grenada, West Indies.
Michael J MontalbanoDepartment of Anatomical Sciences, St. George's University, School of Medicine, Grenada, West Indies.ORCID https://orcid.org/0000-0001-8972-2461
Marios LoukasDepartment of Anatomical Sciences, St. George's University, School of Medicine, Grenada, West Indies.ORCID https://orcid.org/0000-0003-2811-6657

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anatomical descriptions of left-sided oblique coronary branches remain inconsistent, hindering imaging interpretation and surgical planning. To quantify the prevalence, branching patterns and morphometry of the ramus intermedius (RI) and diagonal branches, and propose a unified nomenclature. Following PRISMA guidelines, a PubMed search up to 12 June 2025 yielded 623 records. Forty-six studies involving 25,602 hearts were included, and random-effects meta-analysis was applied to pool prevalence and continuous outcomes. Overall, an additional left-main branch (RI) was present in 25.2% (95% CI: 8.7-54.5). Trifurcation dominated (22.7%), whereas quadrifurcation and pentafurcation occurred in 3.7% and 1.3% respectively. The pooled RI/diagonal diameter averaged 2.21 mm (95% CI 2.02-2.39), and mean branch length was 49.1 mm (95% CI 37.8-60.5). Methodological heterogeneity was high but consistent patterns emerged across cadaveric and imaging modalities. An oblique "diagonal artery", whether arising from the left main (RI) or anterior interventricular artery, is present in roughly 25% of hearts, averages 2.2 mm in caliber and extends to 49 mm. Recognizing this vessel family and standardizing the term "diagonal arteries" will improve coronary imaging reporting and guide revascularization strategies.

Indexed as

Coronary Vessel AnomaliesCoronary VesselsHeartTerminology as TopicAdultChildHumanscoronary angiographycoronary artery trifurcationcoronary vesselsdiagonal coronary arteryramus intermedius

Identifiers

PMID41175009
PMCPMC12988317

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.