Evidence map›Paper›PMID 41174808›Full record

ArticleJournal of medical case reports2025

Malignant paraganglioma of the vagus nerve: diagnostic and therapeutic strategies-a case report.

Messaoudi Karim, Walid Yacine Mohamed Cherif

Abstract readCase Reports
In one paragraph

Article in Journal of medical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Messaoudi KarimDepartment of Medicine, University of Kasdi Merbah, Ouargla, Algeria. messaoudi_karim@hotmail.fr.ORCID http://orcid.org/0000-0003-2339-253X
Walid Yacine Mohamed CherifENT Department, Army Central Hospital, Algiers, Algeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVagal paragangliomas are rare neuroendocrine tumors of the parapharyngeal space, with a small subset exhibiting malignant behavior. Their diagnosis and management remain challenging owing to anatomical complexity and risk of cranial nerve morbidity. CASE PRESENTATION: We report a 46-year-old Maghrebine woman presenting with severe dysphagia and a right lateral cervical mass. Imaging revealed a 40.2 × 40 × 20.6 mm right poststyloid parapharyngeal mass. Surgical excision was performed. Histopathology confirmed metastatic paraganglioma with lymph node involvement, establishing malignancy by current criteria. The patient was referred for adjuvant chemoradiotherapy.

conclusionMalignant vagal paragangliomas require a multidisciplinary approach combining surgery and adjuvant therapies. Genetic testing and long-term follow-up are essential given the risk of metastasis and familial syndromes.

Indexed as

Cranial Nerve NeoplasmsParagangliomaVagus NerveVagus Nerve DiseasesChemoradiotherapy, AdjuvantDeglutition DisordersFemaleHumansLymphatic MetastasisMiddle AgedHead and neck tumorMalignantParapharyngeal spaceVagal paraganglioma

Identifiers

PMID41174808
PMCPMC12577277

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.