Evidence map›Paper›PMID 41174738›Full record

ArticleInternational journal for equity in health2025

Burden and forecast of severe periodontitis in BRICS-Plus nations: trends from 1990 to 2040.

Li-Sha Luo, Jiao Huang, Hang-Hang Luan, Lan Wu, Wen-Zhong Xie, Xian-Tao Zeng, Xia Zhou, Lan Yang, Yuan-Yuan Zhang

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Article in International journal for equity in health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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9 authors.

Li-Sha Luo *Center for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Jiao Huang *Center for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Hang-Hang Luan *Department of Forensic Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Lan WuDepartment of Stomatology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Wen-Zhong XieHenan Provincial Engineering Research Center for Microecological Regulatory of Oral Environment and Oral Implantology, Kaifeng University Health Science Center, Kaifeng, 475000, China.
Xian-Tao ZengCenter for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Xia ZhouDepartment of Stomatology, Daping Hospital, Army Medical University, Chongqing, 400042, China. zhoux20020549@163.com.
Lan YangDivision of Medical Affairs, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China. 413366573@qq.com.
Yuan-Yuan ZhangCenter for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China. zhangyy_ph@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSevere periodontitis is a global public health challenge, disproportionately affecting low- and middle-income countries. BRICS-Plus nations (35 emerging economies representing > 50% world population) face unique pressures from socioeconomic inequalities and aging populations, yet their epidemiological trends remain understudied. This study aims to quantify the burden of severe periodontitis and project future trends in these nations.

methodsUsing data from the Global Burden of Disease Study 2021 (GBD 2021), we analyzed historical trends (1990-2021) of incidence and years lived with disability (YLDs) via the estimated annual percentage change (EAPC). A Bayesian age-period-cohort (BAPC) model was used to generate future projections (2022-2040) that comprehensively account for age, period, and cohort effects.

resultsIn 2021, BRICS-Plus contributed 62.52% of global incident cases (89.61 million) and 64.31% of YLDs (6.90 million). Regional disparities were pronounced: Mercosur and SAARC showed the highest age-standardized burdens (incidence: 1132.20/100,000; YLD: 95.52/100,000), while SACU had the lowest (incidence: 600.50/100,000; YLD: 36.78/100,000). Laos exhibited the sharpest historical rises (incidence EAPC = 1.33, 95%CI: 1.02 to 1.65; YLD EAPC = 1.62, 95%CI: 1.18 to 2.06). BAPC projections indicate sustained growth in Laos, with 40-60-year-olds remaining as the high-risk group, while over half of BRICS-Plus nations may experience downward trends by 2040.

conclusionsSevere periodontitis exhibits divergent trends across BRICS-Plus, with Laos facing escalating burden while most nations show projected declines. Implementing targeted interventions-including tailored dental healthcare strengthening in high-prevalence regions and evidence-based preventive strategies targeting vulnerable middle-aged demographics-is essential for effectively addressing these divergent trends and reducing the overall disease burden.

Indexed as

Cost of IllnessPeriodontitisAdolescentAdultAgedBayes TheoremDeveloping CountriesFemaleForecastingGlobal Burden of DiseaseGlobal HealthHumansIncidenceMaleMiddle AgedBRICS-PlusIncidenceProjectionSevere periodontitisYears lived with disability

Identifiers

PMID41174738
PMCPMC12577221

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