Evidence map›Paper›PMID 41174716›Full record

ArticleBMC musculoskeletal disorders2025

Flexion gap discrepancy drives femoral rotational adjustment in robot-assisted TKA: a CPAK-Based phenotypic analysis.

Haoyang Liu, Hongxu Li, Mengran Shen, Debo Yue, Bailiang Wang, Jinhui Ma

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Article in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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3 · Its place in the literature

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1 citing paper in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Haoyang LiuDepartment of Orthopaedic Surgery, Peking University China-Japan Friendship School of Clinical Medicine, Beijing, 100029, China.
Hongxu LiDepartment of Orthopaedic Surgery, Peking University China-Japan Friendship School of Clinical Medicine, Beijing, 100029, China.
Mengran ShenJiangsu Province (Suqian) Hospital, Suqian, 223800, China.
Debo YueDepartment of Orthopaedic Surgery, Center for Osteonecrosis and Joint Preserving & Reconstruction, China-Japan Friendship Hospital, 2 Yinghuadong Road, Chaoyang District, 100029, Beijing, China.
Bailiang WangDepartment of Orthopaedic Surgery, Peking University China-Japan Friendship School of Clinical Medicine, Beijing, 100029, China. wang_orthopaedic@126.com.
Jinhui MaDepartment of Orthopaedic Surgery, Center for Osteonecrosis and Joint Preserving & Reconstruction, China-Japan Friendship Hospital, 2 Yinghuadong Road, Chaoyang District, 100029, Beijing, China. 1402317340@qq.com.

Funding

Education and teaching reform research project of Capital Medical University 2023JYY388Elite Medical Professionals project of China-Japan Friendship Hospital NO. ZRJY2021-TD01Excellence & Innovation Initiative of China-Japan Friendship Hospital NO. ZRZC2025-XY C01National High Level Hospital Clinical Research Funding 2025-NHLHCRF-PY-02
6 · The paper itself

Abstract

purposeThis study investigates the correlation between femoral component rotational adjustment strategies and coronal alignment parameters in robot-assisted total knee arthroplasty (TKA), and explores differences among Coronal Plane Alignment of the Knee (CPAK) subtypes.

methodsA retrospective analysis of 100 patients with varus gonarthrosis who underwent robot-assisted total knee arthroplasty (TKA) was conducted. Intraoperative navigation data quantified medial/lateral flexion-extension gaps, physiological external rotation, and femoral rotational adjustments. Preoperative CT-based 3D reconstruction, CPAK classification (types I/IV/VII), and radiographic parameters (HKA, lateral distal femoral angle [LDFA], medial proximal tibial angle [MPTA]) were analysed using one-way ANOVA and multivariate linear regression to identify predictors of rotational adjustments and subtype differences.

resultsPost-adjustment femoral external rotation angles exhibited a unimodal distribution (4.41°±2.28°), with 52% of cases concentrated in the 3°–5° range. This represented a significant increase from preoperative physiological external rotation (3.49°±2.17°, Δ = 1.39°, p < 0.001). No differences in final external rotation were observed among CPAK subtypes (p = 0.356), but type I required greater adjustments than type VII (Δ = 1.46°, p = 0.020). Intraoperative flexion gap discrepancy strongly predicted rotational adjustments (β = 0.342, p < 0.01). Adjusted cases exhibited smaller preoperative MPTA (83.37°±5.17 vs. 85.49°±3.40, p = 0.018) and larger preoperative flexion gap discrepancies (2.56 ± 3.33 vs. 0.86 ± 1.30 mm, p < 0.01).

conclusionRobot-assisted TKA optimizes femoral rotational alignment through dynamic gap balancing, with flexion gap discrepancy serving as the primary determinant for rotational compensation. CPAK classification provides preoperative identification of phenotypes requiring specific compensatory strategies, particularly type I deformities which necessitate greater external rotation adjustments. Robotic systems minimize alignment outliers and reduce soft-tissue releases, supporting the adoption of personalized, gap-balancing protocols in TKA.

Indexed as

Arthroplasty, Replacement, KneeFemurKnee JointOsteoarthritis, KneeRobotic Surgical ProceduresAgedAged, 80 and overFemaleHumansMaleMiddle AgedPhenotypeRange of Motion, ArticularRetrospective StudiesRotationCPAK classificationDynamic planningFemoral rotational alignmentGap balancingJapanRobot-assisted total knee arthroplasty

Identifiers

PMID41174716
PMCPMC12577204

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.