ArticleEuropean journal of medical research2025
Association between chronic pain severity, falls, frailty and perceived health in older adults at risk of falls.
Article in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Modulation of the nociceptive withdrawal reflex in walking is not changed by the presence of tonic pain.Experimental brain research · 2026Article
- The association between health-related quality of life and the meaning of life in community-dwelling older adults.BMC geriatrics · 2026Article
- Use of pain neuroscience education, balance evaluation, and exercise for treating chronic pain with kinesiophobia: a narrative review with clinical recommendations.Frontiers in public health · 2026Review
- A Preliminary Predictive Panel for Pre-Frailty Based on Serum Proteomic Biomarkers: A Two-Phase Cross-Sectional Study.Clinical interventions in aging · 2026Article
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Abstract
backgroundChronic pain, defined as pain persisting for ≥ 3 months, is associated with frailty, falls, and reduced quality of life. Falls remain a major cause of morbidity and mortality in older adults, yet the value of integrating pain severity into falls risk assessment is underexplored. This study examined associations between chronic pain severity and subsequent falls, frailty, physical performance, and perceived health in older adults at risk of falls.
methodsIn this cross-sectional study, baseline data from 143 community-dwelling adults aged ≥ 60 years at risk of falls were analysed. Participants were recruited from community and primary care centres in Singapore. Pain severity was assessed using the Wong-Baker Faces Pain Rating Scale (0-10) and classified as no pain, mild pain (< 3), or at least moderate pain (≥ 3). Data on demographics, frailty, sarcopenia (SARC-F ≥ 2), nutrition, cognition, fear of falling, and perceived health (EuroQol Visual Analogue Scale [EQ-VAS] and EuroQoL 5-Dimensions [EQ-5D]) were collected. Physical performance tests included handgrip strength, gait speed, 5-times sit-to-stand, and Timed-Up-and-Go (TUG). Logistic and linear regression models examined associations between pain severity and outcomes, adjusting for demographic and clinical covariates.
resultsChronic pain was prevalent in 37.1%. Compared with no pain, at least moderate pain was associated with higher odds of future falls (adjusted odds ratio (aOR) 3.54, 95% CI 1.53-8.19), moderate/high falls risk (aOR 4.78, 95% CI 1.65-10.77), frailty (aOR 4.17, 95% CI 1.42-8.26), sarcopenia (aOR 4.99, 95% CI 1.63-7.28), slower gait speed (aOR 3.87, 95% CI 1.18-8.67), longer TUG (aOR 4.52, 95% CI 1.36-10.01), and poor physical performance (aOR 12.50, 95% CI 3.94-17.17). Pain severity was associated with EQ-VAS (β = - 4.07, 95% CI - 7.67 to - 1.47) and EQ-5D index (β = - 0.11, 95% CI - 0.15 to - 0.07).
conclusionHigher chronic pain severity was associated with future falls, frailty, poor physical performance and lower perceived health in at-risk older adults. Incorporating pain severity assessment into falls risk stratification could support earlier, targeted interventions to prevent injurious falls. Longitudinal studies are needed to determine the causal impact of pain management on falls, frailty, and quality of life. CLINICAL RELEVANCE: Chronic pain in older adults is significantly associated with an increased risk of future falls, frailty, poor physical performance, and lower perceived health, highlighting the importance of evaluating chronic pain in fall risk assessments and vice versa. Implementing targeted prevention measures for individuals with chronic pain can potentially mitigate the risk of falls and improve overall health outcomes in this population.
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