Evidence map›Paper›PMID 41174709›Full record

ArticleEuropean journal of medical research2025

Association between chronic pain severity, falls, frailty and perceived health in older adults at risk of falls.

Denishkrshna Anbarasan, Reshma Aziz Merchant

Abstract read
In one paragraph

Article in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Denishkrshna AnbarasanDepartment of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, 119228.
Reshma Aziz MerchantDepartment of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, 119228. reshmaa@nuhs.edu.sg.

Funding

Ministry of Health, Singapore MOH/NIC/F2/2017
6 · The paper itself

Abstract

backgroundChronic pain, defined as pain persisting for ≥ 3 months, is associated with frailty, falls, and reduced quality of life. Falls remain a major cause of morbidity and mortality in older adults, yet the value of integrating pain severity into falls risk assessment is underexplored. This study examined associations between chronic pain severity and subsequent falls, frailty, physical performance, and perceived health in older adults at risk of falls.

methodsIn this cross-sectional study, baseline data from 143 community-dwelling adults aged ≥ 60 years at risk of falls were analysed. Participants were recruited from community and primary care centres in Singapore. Pain severity was assessed using the Wong-Baker Faces Pain Rating Scale (0-10) and classified as no pain, mild pain (< 3), or at least moderate pain (≥ 3). Data on demographics, frailty, sarcopenia (SARC-F ≥ 2), nutrition, cognition, fear of falling, and perceived health (EuroQol Visual Analogue Scale [EQ-VAS] and EuroQoL 5-Dimensions [EQ-5D]) were collected. Physical performance tests included handgrip strength, gait speed, 5-times sit-to-stand, and Timed-Up-and-Go (TUG). Logistic and linear regression models examined associations between pain severity and outcomes, adjusting for demographic and clinical covariates.

resultsChronic pain was prevalent in 37.1%. Compared with no pain, at least moderate pain was associated with higher odds of future falls (adjusted odds ratio (aOR) 3.54, 95% CI 1.53-8.19), moderate/high falls risk (aOR 4.78, 95% CI 1.65-10.77), frailty (aOR 4.17, 95% CI 1.42-8.26), sarcopenia (aOR 4.99, 95% CI 1.63-7.28), slower gait speed (aOR 3.87, 95% CI 1.18-8.67), longer TUG (aOR 4.52, 95% CI 1.36-10.01), and poor physical performance (aOR 12.50, 95% CI 3.94-17.17). Pain severity was associated with EQ-VAS (β = - 4.07, 95% CI - 7.67 to - 1.47) and EQ-5D index (β = - 0.11, 95% CI - 0.15 to - 0.07).

conclusionHigher chronic pain severity was associated with future falls, frailty, poor physical performance and lower perceived health in at-risk older adults. Incorporating pain severity assessment into falls risk stratification could support earlier, targeted interventions to prevent injurious falls. Longitudinal studies are needed to determine the causal impact of pain management on falls, frailty, and quality of life. CLINICAL RELEVANCE: Chronic pain in older adults is significantly associated with an increased risk of future falls, frailty, poor physical performance, and lower perceived health, highlighting the importance of evaluating chronic pain in fall risk assessments and vice versa. Implementing targeted prevention measures for individuals with chronic pain can potentially mitigate the risk of falls and improve overall health outcomes in this population.

Indexed as

Accidental FallsChronic PainFrailtyAgedAged, 80 and overCross-Sectional StudiesFemaleHumansMaleMiddle AgedQuality of LifeRisk FactorsSeverity of Illness IndexSingaporeBack painChronic painFalls riskFrailtyOlder adultsQuality of life

Identifiers

PMID41174709
PMCPMC12577368

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.