Evidence map›Paper›PMID 41174684›Full record

ArticleTrials2025

Parent-guided home skin care for infants via a WeChat platform: a study protocol for a cluster randomized controlled trial.

Tongling Yang, Yuying Chen, Yalan Dou, Mengfan Qiu, Yanchen Wang, Siyuan Jiang, Xiaojing Hu

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06544096 (Evaluation of the Effectiveness of a Neonatal Home Skin Care Guidance Based on We-chat), which is not on this map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06544096 nacompletednot on this map

Evaluation of the Effectiveness of a Neonatal Home Skin Care Guidance Based on We-chat: A Cluster-Randomized Controlled Trial

TypeinterventionalSponsorChildren's Hospital of Fudan UniversityRan2024 to 2025Enrolled692ConditionsInfantsArmsintervention group (WeChat platform + healthcare), control group (routine health education)
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

7 authors.

Tongling Yang *Neonatal Intensive Care Unit of Children's Hospital of Fudan University, Shanghai, China.
Yuying Chen *Neonatal Department of Jinjiang Municipal Hospital (Shanghai Sixth People's Hospital Fujian Campus), Fujian, China.
Yalan DouDepartment of Epidemiology at Children's Hospital, of Fudan University, Shanghai, China.
Mengfan QiuSchool of Nursing, Fudan University, Shanghai, China.
Yanchen WangDepartment of Epidemiology at Children's Hospital, of Fudan University, Shanghai, China.
Siyuan JiangNeonatal Intensive Care Unit of Children's Hospital of Fudan University, Shanghai, China.
Xiaojing HuDepartment of Nursing, Children's Hospital of Fudan University, Shanghai, China. humama2015@126.com.ORCID http://orcid.org/0000-0003-0537-7475

Funding

National Children's Medical Center Subject Leader Development Program EKXDPY202305National Key Research and Development Project of China 2016YFC1000500National Key Research and Development Project of China 2021YFC270100
6 · The paper itself

Abstract

backgroundDiaper dermatitis and eczema are common skin conditions that affect infants with a high incidence rate. The prevention and management of these conditions largely depend on parents' adherence to appropriate home skin care practices, with the effectiveness of these practices closely linked to their accurate and consistent implementation. WeChat, a widely used messaging platform in China, has demonstrated potential in promoting health awareness and self-management strategies. We have developed a WeChat-based parent-guided home skin care scheme for infants, specifically designed to assist parents in managing the skin care of newborns. This study aims to evaluate the effectiveness of parent-guided home skin care administered via the WeChat platform in preventing diaper dermatitis and eczema in infants aged 0-6 months, using a clustered randomized controlled trial design.

methodsThis study will be carried out as a cluster randomized controlled trial in the maternity wards of eight hospitals across China. The randomization sequence will be generated by an independent statistical team using specialized software, allocating each center to either the intervention or control group. Infants born in the participating maternity wards between August 1, 2024, and September 30, 2024, whose parents provide voluntary consent, will be included in the study. The exclusion criteria include newborns who require hospitalization immediately following birth, infants diagnosed with congenital skin disorders, and newborns whose mothers have been diagnosed with a mental illness that compromises their ability to provide care or are suffering from a serious illness necessitating hospitalization. The primary outcome of this study is the incidence of diaper dermatitis in 1-month-old infants. Secondary outcomes include the incidence of diaper dermatitis and eczema at 3 and 6 months of age, the frequency of hospital visits due to skin issues, and the assessment of home skin care knowledge. DISCUSSION: The findings from this study may offer valuable insights into the effectiveness of digital health interventions in guiding parents, particularly through the WeChat platform. These interventions may enhance infant skin care practices and reduce the incidence of common skin conditions during early infancy.

trial registrationClinicalTrials.gov NCT06544096. Registered on June 7, 2024.

Indexed as

Diaper RashEczemaHome Care ServicesInfant CareParentsSkin CareChinaFemaleHumansInfantInfant, NewbornMaleMulticenter Studies as TopicRandomized Controlled Trials as TopicCluster randomized controlled trialHome skin careInfantParent-guidedWeChat platform

Identifiers

PMID41174684
PMCPMC12577233

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.