Evidence map›Paper›PMID 41174673›Full record

ArticleBMC public health2025

Cardiovascular disease risk associated with housing disadvantages among middle-aged and older populations in China: a cohort study.

Chengzhe Tao, Tingya Wan, Jingying Zhu, Zhi Li, Yuna Huang, Mingxue Shu, Shuwen Han, Hong Qian, Qiaoqiao Xu, Yun Fan and 3 more

Abstract read
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Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Chengzhe Tao *State Key Laboratory of Reproductive Medicine, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, 211166, China.
Tingya Wan *State Key Laboratory of Reproductive Medicine, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, 211166, China.
Jingying Zhu *Wuxi Center for Disease Control and Prevention, Nanjing Medical University, Nanjing, 211166, China.
Zhi LiState Key Laboratory of Reproductive Medicine, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, 211166, China.
Yuna HuangState Key Laboratory of Reproductive Medicine, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, 211166, China.
Mingxue ShuState Key Laboratory of Reproductive Medicine, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, 211166, China.
Shuwen HanState Key Laboratory of Reproductive Medicine, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, 211166, China.
Hong QianState Key Laboratory of Reproductive Medicine, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, 211166, China.
Qiaoqiao XuState Key Laboratory of Reproductive Medicine, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, 211166, China.
Yun FanState Key Laboratory of Reproductive Medicine, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, 211166, China.
Xinliang DingWuxi Center for Disease Control and Prevention, Nanjing Medical University, Nanjing, 211166, China. dingxinliang@njmu.edu.cn.
Bing LuWuxi Center for Disease Control and Prevention, Nanjing Medical University, Nanjing, 211166, China. lubin@njmu.edu.cn.
Chuncheng LuWuxi Center for Disease Control and Prevention, Nanjing Medical University, Nanjing, 211166, China. chunchenglu@njmu.edu.cn.

Funding

333 High-level Talent Training Project of the Jiangsu Province (2022) 3-16-425Foundation for Innovative Research Groups of the National Natural Science Foundation of China 82271691Major Program of Wuxi Medical Center, Nanjing Medical University WMCJ202302National Key R&D Program of China 2021YFC2700605Top Talent Support Program for young and middle-aged people of Wuxi Health Committee HB2020098
6 · The paper itself

Abstract

backgroundEvidence for associations of housing disadvantages with cardiovascular disease (CVD) is scarce. This study aimed to assess the association of housing disadvantages with CVD among middle-aged and older populations in China.

methodsWe conducted analyses by data from China Health and Retirement Longitudinal Study, 2011-2018. CVD events were ascertained by self-reported data. A total of 9,843 individuals were included in stroke sub-cohort, and 8,752 individuals were included in heart disease sub-cohort. Cox regression was used to estimate hazard ratio (95% confidence interval (CI)) of housing disadvantages with CVD. Population attributable fractions were calculated through Levin's formula and Monte-Carlo simulation to estimate the CVD incidence associated with housing disadvantages in China.

resultsWe found that using crops (HR = 1.35; 95% CI: 1.08-1.68) and coal fuel (HR: 1.71, 95%CI: 1.40-2.10) as heating energy sources were positively associated with heart disease risk compared to clean fuels. Unsafe sanitation was found to be associated with 43% (HR: 1.43, 95%CI: 1.23-1.66) higher heart disease risk and 30% (HR: 1.30, 95%CI: 1.06-1.60) higher stroke risk, and unsafe water source was positively associated with stroke risk (HR: 1.30, 95%CI: 1.08-1.56). Geographical disparities in CVD cases associated with housing disadvantages at a provincial level were found. Annually 1,380,000 cases (15.1%), 718,000 cases (7.9%), and 1,471,000 cases (16.1%) of heart diseases were associated with coal heating energy use, crop heating energy use, and unsafe sanitation, separately. 360,000 cases (12.1%) and 189,000 cases (6.4%) of strokes were associated with unsafe sanitation and unsafe water sources. Regions with lower socio-economic status had higher PAF.

conclusionsThese findings suggested that housing disadvantages were associated with CVD risk in China and highlighted geographical inequality in cardiovascular diseases associated with housing disadvantages.

Indexed as

Cardiovascular DiseasesHousingAgedChinaCohort StudiesFemaleHumansIncidenceLongitudinal StudiesMaleMiddle AgedRisk FactorsBurden estimationCardiovascular diseasesCHARLSHousing disadvantages

Identifiers

PMID41174673
PMCPMC12576997

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.