ArticleBMC infectious diseases2025
Scedosporium Boydii disseminated infection complicating severe SARS-CoV-2 infection in an immunocompetent patient: a case report.
Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Case report: co-infection ofAME case reports · 2025Article
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3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundDisseminated disease by the fungi Scedosporium is rare in immunocompetent patients and has not been reported in the context of severe SARS-CoV-2 infection. CASE PRESENTATION: A retired, 41-year-old police officer with a history of obesity and arterial hypertensionpresented to the emergency department with acute respiratory hypoxemic failure due to severe SARS-CoV-2 pneumonia. He had no history of intravenous drug use and was HIV negative. He practised home aquarium care, biking, river swimming, and fishing. He reported no recent travel to the sea, lakes, or caves.[JG1] He required prolonged mechanical ventilation and had several documented episodes of ventilator-associated pneumonia due to Pseudomonas aeruginosa and Klebsiella pneumoniae, which later evolved to necrotizing pneumonia, multiple lung abscesses, bronchopleural fistula, empyema and subpleural abscess. Despite sedation withdrawal, he remained unconscious; a brain MRI revealed multiple brain abscesses. Scedosporium boydii (S. boydii) grew on lung and brain abscess cultures. In addition to percutaneous drainage of lung abscesses, he was treated with combined therapy with voriconazole and liposomal amphotericin B, considering a possible synergic effect. Drainage of the multiple brain abscesses was not feasible; thus, radiological progression was documented, leading to the patient´s demise despite five weeks of treatment. [JG1]Revisor 1: The abstract is generally well-written, but I suggest omitting the mention of the patient's hobbies asthis detail is not pertinent to the clinical case being discussed. The abstract should be concise and focused solely on the critical clinical aspects.
conclusionInvasive fungal infections (IFIs) by molds are an emerging condition in patients with COVID-19. Cases of aspergillosis, candidiasis and mucormycosis were increasingly reported during the COVID-19 pandemic. This is the first report of a fatal disseminated infection due to Scedosporium boydii preceded by a severe SARS CoV-2 infection.
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