Evidence map›Paper›PMID 41174328›Full record

ReviewCurrent rheumatology reports2025

Updates on the Role of DXA in the Evaluation and Monitoring of Osteoporosis.

Shahane Anupama, Sian Yik Lim, Marcy B Bolster

Abstract readReview
In one paragraph

Review in Current rheumatology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Prevalence of osteoporosis and low bone mass in men with prostate cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shahane AnupamaDivision of Rheumatology, University of Pennsylvania, Philadelphia, PA, USA. Anupama.Shahane@pennmedicine.upenn.edu.
Sian Yik LimHawaii Pacific Health Medical Group, Honolulu, HI , USA.
Marcy B BolsterDivision of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital , Boston, US.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewOsteoporosis, the most common metabolic bone disease and a global health problem, is the result of abnormal bone architecture and bone loss, leading to bone fragility and an increased risk of fractures. A fragility or low-trauma fracture is the first clinical sign of osteoporosis and is typically associated with a significant risk of future fractures. Practical screening tools and guidelines are critical for fracture prevention. Dual X-ray absorptiometry (DXA) is the gold standard for risk stratification and diagnosis of osteoporosis. In this review, we report recent advances in in DXA screening and bone density evaluation for patients at risk of fragility fracture. RECENT

findingsDXA measures bone density as an absolute measure (g/cm2) and also reports the patient's bone mineral density (BMD) as a comparison to a standard population, which is the basis of the World Health Organization (WHO) classification for osteoporosis. DXA also provides vertebral fracture assessment (VFA), an additional tool to assess vertebral fracture presence and increased fracture risk. Understanding the methodology, reporting, and limitations of DXA use is critical for appropriate utilization of the test. BMD is validated as a predictor of fracture risk and may be used with or without clinical risk factors as part of the FRAX fracture risk assessment tool to accurately assess an individual's fracture risk. In this review, we discuss the role of DXA in screening, diagnosis, and treatment of osteoporosis. We include FRAX and its limitations, trabecular bone score (TBS), quantitative computed tomography (qCT) the American College of Rheumatology (ACR) updates on the management of glucocorticoid-induced osteoporosis, the updated International Society of Clinical Densitometry (ISCD) Position Statements, and report the key features of DXA testing, reporting, and utilization in clinical practice. DXA plays a critical role in BMD evaluation and fracture risk assessment. Appropriate utilization of this tool in clinical practice, through accurate interpretation and application of results, is essential for effective fracture prevention.

Indexed as

Absorptiometry, PhotonOsteoporosisOsteoporotic FracturesBone DensityHumansRisk AssessmentBone mineral density (BMD)Dual x-ray absorptiometry (DXA)Fragility fractureFRAXRisk assessment

Identifiers

PMID41174328
PMCPMC12578744

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.