Evidence map›Paper›PMID 41174259›Full record

SynthesisNeurosurgical review2025

Cervicothoracic dorsal rhizotomy for the management of upper limb spasticity: a systematic review.

Camilla de Laurentis, Corentin Dauleac, Pierre-Aurélien Beuriat, Patrick Mertens

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Neurosurgical review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Pediatric spasticity in Brazil: insights from a neurosurgical referral center.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Camilla de LaurentisPediatric Neurosurgery Unit, Hospices Civils de Lyon, Hôpital Femme Mère Enfant, 59, Bd Pinel, 69003, Lyon, France. camilla.de-laurentis@chu-lyon.fr.ORCID http://orcid.org/0000-0003-1867-7899
Corentin DauleacUniversité Lyon 1, Université Claude Bernard, Lyon, France.
Pierre-Aurélien BeuriatPediatric Neurosurgery Unit, Hospices Civils de Lyon, Hôpital Femme Mère Enfant, 59, Bd Pinel, 69003, Lyon, France.
Patrick MertensUniversité Lyon 1, Université Claude Bernard, Lyon, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lumbar selective dorsal rhizotomy (SDR) is a well-established surgical procedure for managing lower limb spasticity. However, its application for upper limb spasticity remains limited. This systematic review aims to analyze and synthesize the existing literature on cervicothoracic SDR for upper limb spasticity, focusing on surgical techniques, its effectiveness, and associated outcomes. A systematic literature review was conducted in PubMed, Scopus, and the Cochrane Library from inception to 2024, following PRISMA guidelines. Studies reporting at least one new case of cervicothoracic SDR for upper limb spasticity were included. Data extraction encompassed demographics, etiology, surgical details, pre- and postoperative spasticity and motor function assessments, and complications. Descriptive statistics and paired-sample t-tests were applied to assess outcomes, with statistical significance set at p < 0.05. A total of 10 studies (48 patients) met inclusion criteria. The mean age was 20.0 ± 13.3 years, with 60.4% pediatric patients. The most common etiologies were cerebral palsy (52.1%), traumatic brain injury (18.7%), and stroke (16.7%). SDR was unilateral in 75% of cases. The mean follow-up was 14.0 ± 7.3 months. Spasticity significantly decreased in 95.6% of patients (p < 0.001 for all muscle groups). Functional assessments demonstrated significant improvement in fine motor skills (p < 0.001), grasping strength (p = 0.005), and pinch strength (p = 0.003). Sensory deficits were reported in 35.3% of cases postoperatively. Complications included infection (2.1%), long-term neuropathic pain (6.3%), and spasticity recurrence (6.5%). Cervicothoracic SDR appears to be a promising surgical option for managing upper limb spasticity, with a favorable benefit-risk profile. Despite encouraging results, further prospective studies with standardized assessment protocols are required to refine patient selection criteria and optimize surgical outcomes.

Indexed as

Muscle SpasticityRhizotomyUpper ExtremityCerebral PalsyCervical VertebraeHumansThoracic VertebraeTreatment OutcomeSelective dorsal rhizotomySpasticityUpper limb

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.