Evidence map›Paper›PMID 41174240›Full record

ArticleJournal of assisted reproduction and genetics2026

The effect of previous caesarean delivery on cumulative live birth rate in IVF/ICSI cycles.

Lanlan Liu, Lijun Wang, Caihui Ma, Jie Geng, Haixiao Chen, Zhenfang Liu, Xuhong Na, Xiaoming Jiang, Jianzhi Ren, Jiali Cai

Abstract read
In one paragraph

Article in Journal of assisted reproduction and genetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Lanlan Liu *Reproductive Medicine Center, Xiamen University Affiliated Chenggong Hospital, Xiamen, Fujian, 361003, China.ORCID http://orcid.org/0000-0003-2730-5763
Lijun Wang *Xiamen Siming District Xiagang Street Community Health Service Center, Xiamen, Fujian, 361005, China.
Caihui MaReproductive Medicine Center, Xiamen University Affiliated Chenggong Hospital, Xiamen, Fujian, 361003, China.
Jie GengReproductive Medicine Center, Xiamen University Affiliated Chenggong Hospital, Xiamen, Fujian, 361003, China.
Haixiao ChenReproductive Medicine Center, Xiamen University Affiliated Chenggong Hospital, Xiamen, Fujian, 361003, China.
Zhenfang LiuReproductive Medicine Center, Xiamen University Affiliated Chenggong Hospital, Xiamen, Fujian, 361003, China.
Xuhong NaReproductive Medicine Center, Xiamen University Affiliated Chenggong Hospital, Xiamen, Fujian, 361003, China.
Xiaoming JiangReproductive Medicine Center, Xiamen University Affiliated Chenggong Hospital, Xiamen, Fujian, 361003, China.
Jianzhi RenReproductive Medicine Center, Xiamen University Affiliated Chenggong Hospital, Xiamen, Fujian, 361003, China. rjz174@126.com.ORCID http://orcid.org/0000-0003-1735-8941
Jiali CaiReproductive Medicine Center, Xiamen University Affiliated Chenggong Hospital, Xiamen, Fujian, 361003, China. jialicai@xmu.edu.cn.

Funding

High-quality Development Science and Technology Plan Project of Xiamen Health 2024GZL-GG88National Natural Science Foundation of China 22176159Natural Science Foundation of Xiamen 3502Z202373122Xiamen Medical Advantage subspecialty construction project 2018296
6 · The paper itself

Abstract

purposeThe purpose of this study is to investigate the effect of women's caesarean delivery history on IVF/ICSI success by evaluating the cumulative live birth rate per treatment cycle.

methodsA total of 4724 parous patients receiving conventional IVF/ICSI treatment were retrospectively analyzed; patients were divided into the caesarean section delivery group (CS, N = 1415) and the vaginal delivery group (VD, N = 3309) according to whether patients had a previous caesarean section history. According to the presence of caesarean scar defect (PCSD), patients in the CS group were categorized into the previous caesarean scar defect subgroup (PCSD, N = 302) and the non-PCSD subgroup (non-PCSD, N = 1113). Propensity score (PS) matching and the generalized linear model (GLM) were used to adjust for potential confounding factors.

resultsThe cumulative live birth rates in the VD group and CS group were similar both before (60.4% vs. 58.4%, P = 0.219) and after (57.8% vs. 58.4%, P = 0.761) PS matching, and there was also no significant difference in the cumulative live birth rates of patients in PCSD, non-PCSD, VD group, and VD-matched group. Subgroup analysis on patients with different prognoses, age, ovarian response, and BMI also showed that there was no significant difference in cumulative live birth rates in subgroups. Cox regression analysis with adjustments made for important covariates and potential confounding factors showed that there was no significant difference in cumulative live birth rates both in the VD group and CS group before and after PS matching.

conclusionPrevious caesarean delivery history may not impact cumulative live birth rate when compared to patients with previous vaginal delivery in IVF/ICSI cycles.

Indexed as

Cesarean SectionFertilization in VitroLive BirthSperm Injections, IntracytoplasmicAdultBirth RateFemaleHumansPregnancyPregnancy RateRetrospective StudiesClinical outcomesCumulative live birth rateICSIIVFPrevious caesarean delivery

Identifiers

PMID41174240
PMCPMC12831761

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.