ArticleMethods in molecular biology (Clifton, N.J.)2026
In Silico Design of Interacting RNA Sequences Using the MODENA Web Server.
Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
To date, various synthetic RNAs that interact with each other have been proposed to artificially control gene expression. By virtue of efficient secondary structure prediction technologies and powerful optimization algorithms, designing interacting RNAs with functional structures in silico is now possible. In this chapter, we describe the use of a web application to design two interacting RNAs with user-prescribed structural features that are intended to work as a molecular switch to modulate gene expression.
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