Evidence map›Paper›PMID 41174130›Full record

ArticleForensic science, medicine, and pathology2026

Monitoring changes in the eyes - the significance of the post-mortem interval in asphyxia.

Emina Dervišević, Edina Lazović-Salčin, Layan Mattar, Amina Zorlak-Čavčić, Hana Bašić, Muhamed Katica, Emina Kujundžić-Begović, Nadža Kapo-Dolan, Francesco Sessa

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In one paragraph

Article in Forensic science, medicine, and pathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Emina DerviševićFaculty of Medicine, Department of Forensic Medicine, University of Sarajevo, Sarajevo, Bosnia and Herzegovina.ORCID http://orcid.org/0000-0002-9673-4820
Edina Lazović-SalčinFaculty of Medicine, Department of Pathology, University of Sarajevo, Sarajevo, Bosnia and Herzegovina.ORCID http://orcid.org/0000-0002-1885-5934
Layan MattarFaculty of Medicine, University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
Amina Zorlak-ČavčićFaculty of Medicine, Department of Forensic Medicine, University of Sarajevo, Sarajevo, Bosnia and Herzegovina.ORCID http://orcid.org/0009-0006-8006-5243
Hana BašićFaculty of Medicine, University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
Muhamed KaticaVeterinary faculty, Department of Clinical Veterinary Sciences, University of Sarajevo, Zmaja od Bosne 90, Sarajevo, Bosnia and Herzegovina, 71000.ORCID http://orcid.org/0000-0002-8184-0065
Emina Kujundžić-BegovićClinical Center University of Sarajevo, Eye Clinic, Sarajevo, Bosnia and Herzegovina.ORCID http://orcid.org/0000-0002-0702-801X
Nadža Kapo-DolanVeterinary faculty, Department of Clinical Veterinary Sciences, University of Sarajevo, Zmaja od Bosne 90, Sarajevo, Bosnia and Herzegovina, 71000. nadzakapo@gmail.com.ORCID http://orcid.org/0000-0002-9922-8034
Francesco SessaDepartment of Medical, Surgical and Advanced Technologies G.F. Ingrassia, University of Catania, Catania, Italy.ORCID http://orcid.org/0000-0003-0357-8791

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of our research was to determine the progression of postmortem ocular changes, focusing on the retina and sclera, over a specified time period and to assess whether these changes are influenced by environmental or physiological factors. Twelve Wistar rats were divided into four experimental groups based on postmortem interval (PMI): immediate autopsy (control), 24 h, 48 h, and 72 h. The mechanism of death was asphyxia by hanging. Each eye sample was macroscopically and microscopically monitored for retinal and scleral changes depending on the PMI and eye exposure (open vs. closed). The most pronounced ocular changes were observed at the longest PMI, including complete loss of retinal stratification, degeneration of ganglion cells, and infiltration by mononuclear inflammatory cells. Similar degenerative changes were observed in the scleral epithelium, particularly in open eyes. This experimental model provides a foundational framework for studying postmortem ocular changes, particularly in the retina and sclera, and may enhance the accuracy of PMI estimation in forensic investigations.

Indexed as

AsphyxiaPostmortem ChangesRetinaScleraAnimalsForensic PathologyMaleModels, AnimalNeck InjuriesRatsRats, WistarTime FactorsAsphyxiaDeathEyePostmortemTemperature

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.