Evidence map›Paper›PMID 41174102›Full record

ReviewNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2025

The cerebellum beyond motor control: cognitive dysfunction in spinocerebellar ataxias.

Andressa Aline Vieira, Renata Barreto Tenório, Amer Cavalheiro Handam, Hélio Afonso Ghizoni Teive, Carlos Henrique Ferreira Camargo

Abstract readReview
PubMed Publisher
In one paragraph

Review in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Andressa Aline VieiraNeurological Diseases Group, Postgraduate Program in Internal Medicine, Internal Medicine Department, Hospital de Clínicas, Federal University of Paraná, Rua General Osório, 181, 10 andar , Curitiba, Paraná, 80060-000, Brazil.ORCID http://orcid.org/0009-0001-2821-0021
Renata Barreto TenórioNeurological Diseases Group, Postgraduate Program in Internal Medicine, Internal Medicine Department, Hospital de Clínicas, Federal University of Paraná, Rua General Osório, 181, 10 andar , Curitiba, Paraná, 80060-000, Brazil.ORCID http://orcid.org/0000-0002-4802-9430
Amer Cavalheiro HandamDepartment of Psychology, Federal University of Paraná, Curitiba, Paraná, Brazil.ORCID http://orcid.org/0000-0003-0198-7401
Hélio Afonso Ghizoni TeiveMovement Disorders Sector, Neurology Service, Internal Medicine Department, Hospital de Clínicas, Federal University of Paraná, Curitiba, Paraná, Brazil.ORCID http://orcid.org/0000-0003-2305-1073
Carlos Henrique Ferreira CamargoNeurological Diseases Group, Postgraduate Program in Internal Medicine, Internal Medicine Department, Hospital de Clínicas, Federal University of Paraná, Rua General Osório, 181, 10 andar , Curitiba, Paraná, 80060-000, Brazil. chcamargo@uol.com.br.ORCID http://orcid.org/0000-0002-3533-0347

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spinocerebellar ataxias (SCAs) are a group of neurodegenerative disorders primarily characterized by progressive ataxia due to degeneration of the cerebellum and its afferent and efferent pathways. Although cerebellar motor symptoms are the clinical hallmark, considerable phenotypic variability exists across SCA subtypes and among individuals with the same genetic mutation. Depending on the subtype and the extent of cerebellar and extracerebellar involvement, various cognitive domains-including memory, attention, executive function, and language-may also be affected. Notably, the cognitive and limbic functions of the cerebellum are primarily localized to its posterior lobe, where current evidence supports distinct topographic representations. The growing body of literature highlights that cognitive impairment is a prominent and heterogeneous feature of SCAs, with wide variation in severity, affected domains, and progression depending on the underlying genetic subtype.

Indexed as

CerebellumCognitive DysfunctionSpinocerebellar AtaxiasHumansCerebellar Cognitive Affective SyndromeCerebellumCognitive DysfunctionDementiaMental Status and Dementia TestsNeurobehavioral ManifestationsSpinocerebellar ataxias

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.