Evidence map›Paper›PMID 41174085›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025

Multidisciplinary management of persistent severe cancer pain: a collaborative European approach.

Denis Dupoiron, María Luz Padilla, Monica Iorfida, Alejandro Falcon, Matthew R D Brown, Christophe Perruchoud, Xander Zuidema, Vittorio Guardamagna, Carlos Tornero, Christoph Hoefing and 5 more

Abstract read
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Denis DupoironAnesthesiology and Pain. Institut de Cancérologie L'Ouest (ICO), Angers, France. denis.dupoiron@ico.unicancer.fr.
María Luz PadillaLa Tour Hospital, Geneva, Switzerland.
Monica IorfidaOncology. IEO Hospital, Milan, Italy.
Alejandro FalconOncology. Virgen del Rocío Hospital, Seville, Spain.
Matthew R D BrownPain Medicine., Honorary Associate Faculty, The Royal Marsden Hospital, The Institute of Cancer Research, London, UK.
Christophe PerruchoudLa Tour Hospital, Geneva, Switzerland.
Xander ZuidemaAnesthesiology. Diakonessenhuis Zeist Hospital, Zeist, Netherlands.
Vittorio GuardamagnaPalliative Care and Pain Therapy. , IEO Hospital, Milan, Italy.
Carlos TorneroValencia University Hospital, Valencia, Spain.
Christoph HoefingPain Medicine., Kemperhof Day Clinic Pain Therapy , Koblenz, Germany.
Somnath BagchiAnesthesiology and Pain Medicine. , Plymouth Hospitals NHS Trust, Plymouth, UK.
Debora Van KeulenNurse Practitioner. Diakonessenhuis Utrecht Hospital, Utrecht, Netherlands.
Rita KortbaouiAnesthesiology and Pain Medicine. , Gustave Roussy Hospital, Villejuif, France.
Teresa MacarullaOncology. Vall d'Hebrón Hospital, Barcelona, Spain.
Mario Di PalmaOncology. Gustave Roussy Hospital, Villejuif, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeCancer pain is often undertreated, with patients frequently referred late to specialist services. This study aimed to develop expert-led recommendations to address unmet needs in the management of persistent severe cancer pain in Europe.

methodsAn online questionnaire on cancer pain management was used to identify controversies in the clinical practice of European oncologists. A series of recommendations to address these controversies was then proposed and validated, using a Delphi-like methodology, by a joint expert panel of pain specialists and oncologists.

resultsConsensus was reached on 13 recommendations. Key agreements focused on the following: (i) collaboration: establishing cancer pain committees (87% agreement) and shared protocols (100%), (i) education: implementing telematic consultations (100%) and training sessions for oncologists (100%) and (iii) referral: establishing clear referral criteria (100%) for patients with poor quality of life (QoL) (100%) or persistent pain, regardless of aetiology (87-100%), to ensure timely access to specialist care.

conclusionEffective cancer pain management necessitates enhanced collaboration between specialties, targeted education for oncologists, and locally co-created protocols with clear referral criteria. These measures are essential to ensure that patients are referred to pain specialists in a timely and appropriate manner, which is crucial for improving their QoL.

Indexed as

Cancer PainPain ManagementConsensusDelphi TechniqueEuropeHumansOncologistsPatient Care TeamQuality of LifeReferral and ConsultationSurveys and QuestionnairesCancer painClinical practiceDelphi-like methodologyOncology expertPain specialistPersistent severe pain

Identifiers

PMID41174085
PMCPMC12578720

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.