Evidence map›Paper›PMID 41174079›Full record

ArticleNeuroradiology2025

Feasibility, safety and efficacy of Woven EndoBridge embolization of intracranial aneurysms with the 2 mm height variants.

Lukas Goertz, Sophia Hohenstatt, Eberhard Siebert, Hanna Styczen, Alexander Ranft, David Zopfs, Daniel Kaiser, Pawel Krukowski, Marc Schlamann, Jonathan Kottlors and 6 more

Abstract readMulticenter Study
In one paragraph

Article in Neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Lukas GoertzFaculty of Medicine and University Hospital, Department of Radiology and Neuroradiology, University of Cologne, Cologne, Germany. lukas.goertz@uk-koeln.de.
Sophia HohenstattDepartment of Neuroradiology, University Hospital Heidelberg, Heidelberg, Germany.
Eberhard SiebertDepartment of Neuroradiology, University Hospital of Berlin (Charité), Berlin, Germany.
Hanna StyczenInstitute for Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Germany.
Alexander RanftDepartment of Radiology and Neuroradiology, Klinikum Hochsauerland, Arnsberg, Germany.
David ZopfsFaculty of Medicine and University Hospital, Department of Radiology and Neuroradiology, University of Cologne, Cologne, Germany.
Daniel KaiserDepartment of Neuroradiology, University Hospital Dresden, Dresden, Germany.
Pawel KrukowskiDepartment of Neuroradiology, University Hospital Dresden, Dresden, Germany.
Marc SchlamannFaculty of Medicine and University Hospital, Department of Radiology and Neuroradiology, University of Cologne, Cologne, Germany.
Jonathan KottlorsFaculty of Medicine and University Hospital, Department of Radiology and Neuroradiology, University of Cologne, Cologne, Germany.
Jan Paul JanssenFaculty of Medicine and University Hospital, Department of Radiology and Neuroradiology, University of Cologne, Cologne, Germany.
Cornelius DeuschlInstitute for Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Germany.
Franziska DornDepartment of Neuroradiology, University Hospital Bonn, Bonn, Germany.
Markus A MöhlenbruchDepartment of Neuroradiology, University Hospital Heidelberg, Heidelberg, Germany.
Thomas LiebigDepartment of Neuroradiology, University Hospital Munich (LMU), Munich, Germany.
Christoph KabbaschFaculty of Medicine and University Hospital, Department of Radiology and Neuroradiology, University of Cologne, Cologne, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSmall, shallow aneurysms (SSAs) present technical challenges for endovascular treatment with the risk of aneurysm perforation and coil protrusion. The Woven EndoBridge (WEB) device, particularly the lowest height of 2 mm variant, offers a potential alternative option for these aneurysms. This multicenter study evaluates the feasibility, safety and efficacy of the WEB for SSAs ≤ 4.1 mm width.

methodsA total of 103 aneurysms (mean size: 3.4 ± 1.1 mm, 67 [65%] bifurcation) treated with WEB single-layer sizes ranging from 3 × 2 mm to 4.5 × 2 mm were retrospectively analyzed. Data on procedural success, complications, and angiographic outcomes were collected. The incidence and potential strategies to counteract WEB protrusion were evaluated.

resultsWEB deployment was successful in 97 (94%) cases, but WEB protrusion occurred in 12 (12%) cases. Strategies to counteract WEB protrusion were change to another endovascular technique (n = 4), additional stent implantation (n = 4), change to a smaller WEB size (n = 3), and repositioning of the WEB (n = 1). Procedural thromboembolic complications occurred in 4 (4%) cases, of which 3 were due to protrusion of the WEB, but all were asymptomatic. Two hemorrhagic complications (2%), caused by aneurysm perforation with the microwire in the first case and with the folded WEB tip in the second, resulted in procedural morbidity (2%). Complete and adequate occlusion rates were 82% (42/51) and 90% (46/51) at 6 months and 76% (19/25) and 88% (22/25) at 12 months, respectively.

conclusionThe 2 mm height WEB demonstrated feasibility and efficacy in the treatment of SSAs with good safety results, making it a viable alternative endovascular option for SSAs.

Indexed as

Embolization, TherapeuticIntracranial AneurysmAdultAgedCerebral AngiographyFeasibility StudiesFemaleHumansMaleMiddle AgedRetrospective StudiesStentsTreatment OutcomeEndovascularFlow-disruptionIntracranial aneurysmIntrasaccular

Identifiers

PMID41174079
PMCPMC12743084

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.