Evidence map›Paper›PMID 41173945›Full record

ArticleScientific reports2025

Antimicrobial effects and mechanisms of hydrogen sulphide against nail pathogens.

Fritz Ka-Ho Ho, Alyaa Al-Tabtabai, Sara M Nasereddin, Osamah S Malallah, Mark A Lindsay, Stuart A Jones, Albert Bolhuis

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fritz Ka-Ho HoDepartment of Life Sciences, University of Bath, Claverton Down, Bath, BA2 7AY, UK.
Alyaa Al-TabtabaiFaculty of Life Sciences and Medicine, King's College London, Institute of Pharmaceutical Science, Franklin-Wilkins Building, London, UK.
Sara M NasereddinFaculty of Life Sciences and Medicine, King's College London, Institute of Pharmaceutical Science, Franklin-Wilkins Building, London, UK.
Osamah S MalallahFaculty of Life Sciences and Medicine, King's College London, Institute of Pharmaceutical Science, Franklin-Wilkins Building, London, UK.
Mark A LindsayDepartment of Life Sciences, University of Bath, Claverton Down, Bath, BA2 7AY, UK.
Stuart A JonesFaculty of Life Sciences and Medicine, King's College London, Institute of Pharmaceutical Science, Franklin-Wilkins Building, London, UK.
Albert BolhuisDepartment of Life Sciences, University of Bath, Claverton Down, Bath, BA2 7AY, UK. a.bolhuis@bath.ac.uk.

Funding

Engineering and Physical Sciences Research Council EP/V009621/1Engineering and Physical Sciences Research Council EP/VOO9567/1
6 · The paper itself

Abstract

Nail infections are common but challenging to treat. Oral treatments can be effective but may cause adverse effects and drug interactions, while topical treatments only work in about a third of patients due to poor penetration of antifungals into the nail plate. Small polar molecules, such as hydrogen sulphide (H

Indexed as

Anti-Infective AgentsHydrogen SulfideNail DiseasesNailsBacteriaElectron Transport Complex IVFungiHumansMicrobial Sensitivity TestsOnychomycosisReactive Oxygen SpeciesAnti-Infective AgentsElectron Transport Complex IVHydrogen SulfideReactive Oxygen SpeciesAntifungalDermatophyteHydrogen sulphideNail infectionOnychomycosisReactive oxygen species

Identifiers

PMID41173945
PMCPMC12578836

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.