Evidence map›Paper›PMID 41173748›Full record

ReviewTrends in parasitology2025

A guide to the apicomplexan cell cycle: endodyogeny and schizogony.

Mrinalini Batra, Elena S Suvorova

Abstract readReview
In one paragraph

Review in Trends in parasitology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mrinalini BatraDivision of Infectious Diseases and International Medicine, Department of Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL 33612, USA.
Elena S SuvorovaDivision of Infectious Diseases and International Medicine, Department of Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL 33612, USA. Electronic address: suvorova@usf.edu.

Funding

Regulation of apicomplexan mitosis coupled to buddingR01AI175640 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI Elena Suvorova · 2024 to 2026
$1.6M
Deciphering the composite S-phase in Toxoplasma gondiiR21AI178797 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI SUVOROVA, ELENA · 2023 to 2024
$413k
New reporter system for spatiotemporal visualization of Toxoplasma gondii growth and developmentR03AI155834 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI SUVOROVA, ELENA · 2021 to 2022
$150k
NIAID NIH HHS R01 AI175640NIAID NIH HHS R03 AI155834NIAID NIH HHS R21 AI178797
6 · The paper itself

Abstract

This review focuses on recent advances in the field of cell division of eukaryotic pathogens of the phylum Apicomplexa, a group of pathogens known for their diverse modes of cell division. We cover two topics - an organization and a regulation of the apicomplexan cell cycles - using models of Toxoplasma gondii tachyzoites and Plasmodium falciparum merozoites of the red blood cell stage. The review emphasizes differences and similarities between the conventional cell cycle of the parasite's host cells and apicomplexan cell cycles, and between binary and multinuclear divisions of Apicomplexa. Although many factors play a role in cell cycle regulation, we concentrated on the central cell cycle regulators, cyclin-dependent kinase complexes.

Indexed as

ApicomplexaCell CyclePlasmodium falciparumToxoplasmaAnimalsHumansLife Cycle StagesApicomplexacell cycleendomitosis cyclin-dependent kinasePlasmodiumToxoplasma gondii

Identifiers

PMID41173748
PMCPMC13628307

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.