ArticleJACC. Case reports2025
Congenital Pericardial Agenesis Diagnosed at Advanced Age and Treated Via Minimally Invasive Repair.
Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundCongenital absence of the pericardium is a rare condition, usually detected incidentally and often asymptomatic. Symptomatic cases are uncommon, and they pose diagnostic and therapeutic challenges. CASE SUMMARY: A 65-year-old man presented with exertional chest discomfort that varied with body position. Transthoracic echocardiography suggested a pericardial defect. Chest computed tomography and cardiac magnetic resonance imaging confirmed complete congenital absence of the pericardium. Thoracoscopic minimally invasive repair without cardiopulmonary bypass or blood transfusion relieved his symptoms. DISCUSSION: This case highlights the diagnostic value of multimodal imaging and the feasibility of minimally invasive repair in older patients with symptomatic pericardial agenesis. TAKE-HOME MESSAGES: Although complete pericardial agenesis is often asymptomatic, surgery may be warranted in symptomatic cases, even in older patients. Thoracoscopic minimally invasive repair without cardiopulmonary bypass or blood transfusion is a feasible approach.
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