Evidence map›Paper›PMID 41173509›Full record

ArticleGenome research2026

Predicted protein 3D structures provide essential insights into the genetic architecture underlying phenotypic diversity in maize.

Shuai Wang, Merritt Khaipho-Burch, Lynn C Johnson, Zachary R Miller, Peter J Bradbury, Doug Speed, William J Allen, M Cinta Romay, Jiquan Xue, Edward S Buckler and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genome research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shuai WangKey Laboratory of Maize Biology and Genetic Breeding in Arid Areas of the Northwest Region, College of Agronomy, Northwest A&F University, Yangling, Shaanxi 712100, China.
Merritt Khaipho-BurchSection of Plant Breeding and Genetics, Cornell University, Ithaca, New York 14853, USA.
Lynn C JohnsonInstitute for Genomic Diversity, Cornell University, Ithaca, New York 14853, USA.
Zachary R MillerInstitute for Genomic Diversity, Cornell University, Ithaca, New York 14853, USA.
Peter J BradburyAgricultural Research Service, United States Department of Agriculture, Ithaca, New York 14853, USA.
Doug SpeedCenter for Quantitative Genetics and Genomics, Aarhus University, Aarhus 8000, Denmark.ORCID 0000-0002-0096-9765
William J AllenTexas Advanced Computing Center, University of Texas at Austin, Austin, Texas 78758, USA.
M Cinta RomayInstitute for Genomic Diversity, Cornell University, Ithaca, New York 14853, USA.
Jiquan XueKey Laboratory of Maize Biology and Genetic Breeding in Arid Areas of the Northwest Region, College of Agronomy, Northwest A&F University, Yangling, Shaanxi 712100, China.
Edward S BucklerSection of Plant Breeding and Genetics, Cornell University, Ithaca, New York 14853, USA.
Guillaume P RamsteinCenter for Quantitative Genetics and Genomics, Aarhus University, Aarhus 8000, Denmark; bs674@cornell.edu ramstein@qgg.au.dk.ORCID 0000-0002-7536-1113
Baoxing SongKey Laboratory of Maize Biology and Genetic Breeding in Arid Areas of the Northwest Region, College of Agronomy, Northwest A&F University, Yangling, Shaanxi 712100, China; bs674@cornell.edu ramstein@qgg.au.dk.ORCID 0000-0003-1478-9228

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Variation in protein 3D structures reflects genetic variation and contributes to phenotypic diversity, yet its underlying genetic mechanisms remain unclear. To investigate the relationship between protein 3D structure and phenotype, we predict the 3D structures of 795,649 proteins from 26 maize (

Indexed as

Genetic VariationPlant ProteinsZea maysEvolution, MolecularGenome, PlantGenome-Wide Association StudyHaplotypesPhenotypeProtein ConformationPlant Proteins

Identifiers

PMID41173509
PMCPMC12758397

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.