Evidence map›Paper›PMID 41172913›Full record

ArticleJournal of magnetic resonance (San Diego, Calif. : 1997)2025

A steady-state approach for analysis of high-resolution relaxometry.

Shibani Bhattacharya, Michael Goger, Tassadite Dahmane, Arthur G Palmer

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of magnetic resonance (San Diego, Calif. : 1997), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. High-Resolution Relaxometry for Fragment Screening.Journal of medicinal chemistry · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shibani BhattacharyaNew York Structural Biology Center, 89 Convent Avenue, New York, NY 10027, United States of America. Electronic address: sbhattacharya@nysbc.org.
Michael GogerNew York Structural Biology Center, 89 Convent Avenue, New York, NY 10027, United States of America. Electronic address: mgoger@nysbc.org.
Tassadite DahmaneNew York Structural Biology Center, 89 Convent Avenue, New York, NY 10027, United States of America. Electronic address: tdahmane@nysbc.org.
Arthur G PalmerDepartment of Biochemistry and Molecular Biophysics, Columbia University, 701 West 168th Street, New York, NY 10032, United States of America. Electronic address: agp6@columbia.edu.

Funding

RM1 Center on Macromolecular Dynamics by NMR Spectroscopy at the New York Structural Biology Center (CoMD/NMR)- Equipment Supplement RequestRM1GM145397 · NIGMS · NEW YORK STRUCTURAL BIOLOGY CENTER · PI ARTHUR G PALMER · 2022 to 2026
$8.3M
900 MHz NMR Spectrometer for Structural BiologyP41GM066354 · NIGMS · NEW YORK STRUCTURAL BIOLOGY CENTER · PI COWBURN, DAVID · 2002 to 2006
$4.7M
Acquisition of a 900 MHz NMR Spectrometer Console and ProbesS10OD030373 · OD · NEW YORK STRUCTURAL BIOLOGY CENTER · PI PALMER, ARTHUR G · 2021 to 2021
$1.7M
Acquisition of 700 MHz NMR SpectrometerS10OD018509 · OD · NEW YORK STRUCTURAL BIOLOGY CENTER · PI PALMER, ARTHUR G · 2015 to 2015
$1.1M
475 MHz NMR SpectrometerS10OD023499 · OD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI PALMER, ARTHUR G · 2017 to 2017
$925k
NIGMS NIH HHS P41 GM066354NIGMS NIH HHS RM1 GM145397NIH HHS S10 OD018509NIH HHS S10 OD023499NIH HHS S10 OD030373
6 · The paper itself

Abstract

High-resolution relaxometry measures nuclear spin longitudinal relaxation rate constants at low static magnetic field, either in the fringe field of a high-field NMR magnet or in an external electromagnetic coil, while polarizing and detecting nuclear magnetization at high field to optimize resolution and sensitivity for biological macromolecules. Detected magnetization depends on relaxation in the low magnetic field and on relaxation during transfer to and from the high magnetic field. Relaxation for backbone amide

Indexed as

Nuclear Magnetic Resonance, BiomolecularAlgorithmsAmidesAnisotropyElectromagnetic FieldsMagnetic FieldsMagnetic Resonance SpectroscopyNitrogen IsotopesProteinsUbiquitinAmidesNitrogen IsotopesProteinsUbiquitinField cyclingModel-free formalismOrder parameterRotational diffusionSample shuttleSpectral density

Identifiers

PMID41172913
PMCPMC13123869

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.